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Use of antipsychotic medications for the management of delirium: an audit of current practice in the acute care setting

Published online by Cambridge University Press:  05 November 2008

J. Tropea*
Affiliation:
Clinical Epidemiology and Health Service Evaluation Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia
J. Slee
Affiliation:
Clinical Epidemiology and Health Service Evaluation Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia
A. C. N. Holmes
Affiliation:
Department of Psychiatry, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia
A. Gorelik
Affiliation:
Clinical Epidemiology and Health Service Evaluation Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia
C. A. Brand
Affiliation:
Clinical Epidemiology and Health Service Evaluation Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia and NHMRC Centre for Research Excellence in Patient Safety (CREPS), Monash University, The Alfred Hospital, Melbourne, Australia
*
Correspondence should be addressed to: Joanne Tropea, Clinical Epidemiology and Health Service Evaluation Unit, Royal Melbourne Hospital, 34–54 Poplar Road, Parkville, Victoria, Australia3052. Phone: +61 03 9342 8772; Fax: +61 03 9342 7060. Email: Joanne.Tropea@mh.org.au

Abstract

Objective: Despite delirium being common in older hospitalized people, little is known about its management. The aims of this study are (1) to describe the pharmacological management of delirium in an acute care setting as a baseline measure prior to the implementation of newly developed Australian guidelines; and (2) to determine what areas of delirium pharmacological management need to be targeted for future practical guideline implementation and quality improvement activities.

Methods: A medical record audit was conducted using a structured audit form. All patients aged 65 years and over who were admitted to a general medical or orthopaedic unit of the Royal Melbourne Hospital between 1 March 2006 and 28 February 2007 and coded with delirium were included. Data on the use of antipsychotic medications for the management of delirium in relation to best practice recommendations were assessed.

Results: Overall 174 episodes of care were included in the analysis. Antipsychotic medications were used for the management of most patients with severe behavioral and or emotional disturbance associated with delirium. There was variation in the prescribing patterns of antipsychotic agents and the documentation of medication management plans. Less than a quarter of patients prescribed antipsychotic medication were started on a low dose and very few were reviewed on a regular basis.

Conclusion: A wide range of practice is seen in the use of antipsychotic agents to manage older patients with severe symptoms associated with delirium. The findings highlight the need to implement evidence-based guideline recommendations with a focus on improving the consistency in the pharmacological management and documentation processes.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2008

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References

American Psychiatric Association (1999). Practice guidelines for the treatment of patients with delirium. American Journal of Psychiatry, 156, 120.Google Scholar
Australian Society for Geriatric Medicine (2005). Australian Society for Geriatric Medicine Position statement No. 2 Physical restraint use in older people. Revised 2005. [cited 27 November 2007]. Available at: http://www.asgm.org.au/documents/POSITIONSTATEMENTNO2.PhysicialRestraint-Revision.pdfGoogle Scholar
Bethell, D. L., Myers, W. A. and Smith, D. G. (2000) Does patient-centered care pay off? Joint Commission Journal on Quality Improvement, 26, 400409.Google Scholar
Bruce, A. J., Ritchie, C. W., Blizard, R., Lai, R. and Raven, P. (2007). The incidence of delirium associated with orthopedic surgery: a meta-analytic review. International Psychogeriatrics, 19, 197214.CrossRefGoogle ScholarPubMed
Clinical Epidemiology and Health Service Evaluation Unit, Melbourne Health and the Australian Health Ministers' Health Care of Older Australians Standing Committee (2006). Clinical Practice Guidelines for the Management of Delirium in Older People, October 2006. Available at: http://www.health.vic.gov.au/acute-agedcare/Google Scholar
Cole, M. G. and Primeau, F. J. (1993). Prognosis of delirium in elderly hospital patients. Canadian Medical Association Journal, 149, 4146.Google ScholarPubMed
Conn, D. K. and Madan, R. (2006). Use of sleep-promoting medications in nursing home residents: risks versus benefits. Drugs and Aging, 23, 271287.CrossRefGoogle ScholarPubMed
Cook, I. A. (2004). Guideline Watch: Practice Guideline for the Treatment of Patients with Delirium. DOI: 10.1176/appi.books.9780890423363.147844. Available at: http://www.psychiatryonline.com/content.aspx?aid=147844.Google Scholar
Elie, M., Cole, M. G., Primeau, F. J. and Bellavance, F. (1998). Delirium risk factors in elderly hospitalized patients. Journal of General Internal Medicine, 13, 204212.CrossRefGoogle ScholarPubMed
Galanakis, P., Bickel, H., Gradinger, R., Von Gumppenberg, S. and Förstl, H. (2001). Acute confusional state in the elderly following hip surgery: incidence, risk factors and complications. International Journal of Geriatric Psychiatry, 16, 349355.CrossRefGoogle ScholarPubMed
Inouye, S. K., Foreman, M. D., Mion, L. C., Katz, K. H. and Cooney, L. M. (2001). Nurses' recognition of delirium and its symptoms: comparison of nurse and researcher ratings. Archives of Internal Medicine, 161, 24672473.CrossRefGoogle ScholarPubMed
Inouye, S. K., Rushing, J. T., Foreman, M. D., Palmer, R. M. and Pompei, P. (1998). Does delirium contribute to poor hospital outcomes? A three-site epidemiologic study. Journal of General Internal Medicine, 13, 234242.CrossRefGoogle ScholarPubMed
Iseli, R. K., Brand, C., Telford, M. and LoGiudice, D. (2007). Delirium in elderly general medical inpatients: a prospective study. Internal Medicine Journal. 37, 806811. doi: 10.1111/j.1445–5994.2007.01386.x.CrossRefGoogle ScholarPubMed
Joanna Briggs Institute (2002). Physical restraint – Part 1: Use in acute and residential care facilities. Best Practice, 6, 16. Available at: http://www.joannabriggs.edu.au/pdf/BPISEng_6_3.pdfGoogle Scholar
Kirkwood, B. R. and Sterne, J. A. C. (2003) Essential Medical Statistics. 2nd edn. Massachusetts: Blackwell Science Ltd.Google Scholar
Lingard, L. et al. (2005). Communication failures in the operating room: an observational classification of recurrent types and effects. Quality and Safety in Health Care, 13, 330334.CrossRefGoogle Scholar
Marcantonio, E. R., Flacker, J. M., Michaels, M. and Resnick, N. M. (2000). Delirium is independently associated with poor functional recovery after hip fracture. Journal of the American Geriatrics Society, 48, 618624.CrossRefGoogle ScholarPubMed
Marcantonio, E. R. et al. (1998). The association of intraoperative factors with the development of postoperative delirium. American Journal of Medicine, 105, 380384.CrossRefGoogle ScholarPubMed
National Prescribing Service Limited (2007). What's “atypical” about the newer antipsychotics? NPS News, 51. Available at: http://www.nps.org.au/site.php?content=/html/news.php&news=/resources/NPS_News/news51Google Scholar
Rossi, S. and Edwards, S. (eds.) (2003). Australian Medicines Handbook Drug Choice Companion: Aged Care. Adelaide: Commonwealth Department of Health and Ageing, Commonwealth Department of Veterans' Affairs.Google Scholar
Ski, C. and O'Connell, B. (2006). Mismanagement of delirium places patients at risk. Australian Journal of Advanced Nursing, 23, 4246.Google ScholarPubMed
Stevens, L. E., de Moore, G. M. and Simpson, J. M. (1998). Delirium in hospital: does it increase length of stay? Australian and New Zealand Journal of Psychiatry, 32, 805808.CrossRefGoogle ScholarPubMed