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An investigation of the efficiency of the mini-Kingston standardized cognitive assessment-revised in classifying patients according to DSM-5 major and mild neurocognitive disorders due to possible Alzheimer's disease

Published online by Cambridge University Press:  19 January 2015

Jeremia Heinik  and
Gitit Kavé
Jeremia Heinik*
Affiliation:
Margoletz Psychogeriatric Center, Ichilov Hospital, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Gitit Kavé
Affiliation:
Margoletz Psychogeriatric Center, Ichilov Hospital, Tel Aviv, Israel Department of Education and Psychology, The Open University, Ra'anana, Israel
*
Correspondence should be addressed to: Jeremia Heinik, Margoletz Psychogeriatric Center, Ichilov Hospital, 6 Weizmann Street, Tel Aviv, 6423906, Israel. Phone: +972-3-6973325; Fax: +972-3-6974658. Email: heinik@post.tau.ac.il.
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Abstract

Background:

The aim of this study was to examine the efficiency of the mini-Kingston standardized cognitive assessment-revised (mini-KSCAr) in classifying patients according to DSM-5 major and mild neurocognitive disorders (NCD) due to possible Alzheimer's disease (AD).

Methods:

Files of 85 individuals who were tested on the Kingston standardized cognitive assessment-revised were reviewed and scores were calculated for the mini-KSCAr. Medical history, psychiatric and physical status, basic and instrumental activities of daily living, as well as scores on the Cambridge cognitive examination-revised (CAMCOG-R), and the clinical dementia rating (CDR) scale were used to establish DSM-5 diagnoses of major or mild neurocognitive disorders (NCD) due to possible AD or no cognitive decline. All participants were tested on the Mini-Mental State Examination (MMSE) and the clock drawing test (CDT), and a subset (N = 28) were also tested on three well-known memory tasks.

Results:

Scores on the MMSE, CDT, and mini-KSCAr differed across groups, but only the mini-KSCAr significantly distinguished each group from the other two. The mini-KSCAr showed better sensitivity, specificity, and likelihood ratios (LRs) than did the MMSE and the CDT. A regression analysis revealed that the mini-KSCAr accounted for almost half of the variance in memory performance, whereas the MMSE and the CDT contributed nothing to this prediction once the mini-KSCAr was used.

Conclusions:

The mini-KSCAr is an efficient instrument for the diagnosis of DSM-5 major and mild NCD due to possible AD in a specialized psychogeriatric setting, and its utility is greater than that of the MMSE and the CDT.

Keywords

dementiascreening testscognitive evaluationAlzheimer’s disease
Type
Research Article
Information
International Psychogeriatrics , Volume 27 , Issue 5 , May 2015 , pp. 785 - 791
Copyright
Copyright © International Psychogeriatric Association 2015 

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