Skip to main content Accessibility help
×
Home
Hostname: page-component-55b6f6c457-hjh89 Total loading time: 0.331 Render date: 2021-09-26T14:11:13.726Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Retrospective Diagnosis of Dementia Using an Informant Interview Based on the Brief Cognitive Rating Scale

Published online by Cambridge University Press:  10 January 2005

Kenneth Rockwood
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.
Kellee Howard
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.
Vince Salazar Thomas
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.
Laurie Mallery
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.
Christopher Macknight
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.
Virgilio Sangalang
Affiliation:
Department of Pathology, Dalhousie University, Halifax, Canada.
Sultan Darvesh
Affiliation:
Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Canada.

Abstract

The accuracy of a dementia diagnosis by specialist physicians, as verified at an autopsy, is greater than 90% in many series. Donations of brains to the Maritime Brain Tissue Bank (MBTB) by individuals who did not have expert dementia diagnoses before death led us to investigate whether clinical features could also be detected retrospectively. Informants for 36 individuals whose brains were in the MBTB (18 women, mean age = 79 years; pathologic diagnoses: 75% Alzheimer's disease [AD]; 8.4% vascular or mixed dementia) were interviewed by specialist physicians using a semistructured retrospective interview based on the Brief Cognitive Rating Scale (BCRS) (range = 1 [no impairment] to 7 [terminal dementia]). The mean duration of dementia was 8.5 ± 12.8 years based on proxy reports, and most cases suggested severe dementia—(stage 6 [severe] or 7 [terminal])—on the retrospective BCRS (RetroBCRS) before death. A score of 4 or more on the RetroBCRS had 100% sensitivity and specificity in detecting dementia. The RetroBCRS score correlated moderately with duration (.51). In linear and logistic regression models adjusted for age and sex, RetroBCRS staging helped explain 93% of the variation in duration. The accuracy of the retrospective diagnosis of the cause of dementia, compared with autopsy, was 92%. The RetroBCRS used by an expert physician with a reliable informant is a valid method of detecting dementia and determining whether AD was present.

Type
Dementia
Copyright
© 1998 International Psychogeriatric Association

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)
23
Cited by

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Retrospective Diagnosis of Dementia Using an Informant Interview Based on the Brief Cognitive Rating Scale
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Retrospective Diagnosis of Dementia Using an Informant Interview Based on the Brief Cognitive Rating Scale
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Retrospective Diagnosis of Dementia Using an Informant Interview Based on the Brief Cognitive Rating Scale
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *