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Single Preoperative Bladder Instillation of Povidone-Iodine for the Prevention of Postprostatectomy Bacteriuria and Wound Infection

Published online by Cambridge University Press:  21 June 2016

Santiago Richter ,
Oscar Kotliroff  and
Israel Nissenkorn
Santiago Richter*
Affiliation:
Department of Urology, Sapir Medical Center, Kfar Saba, and Sackler School of Medicine, Tel-Aviv University, Israel
Oscar Kotliroff
Affiliation:
Department of Urology, Sapir Medical Center, Kfar Saba, and Sackler School of Medicine, Tel-Aviv University, Israel
Israel Nissenkorn
Affiliation:
Department of Urology, Sapir Medical Center, Kfar Saba, and Sackler School of Medicine, Tel-Aviv University, Israel
*
Department of Urology, Sapir Medical Center, 44281 Kfar Saba, Israel
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Abstract

Objective:

To study the effectiveness of preoperative bladder washing with povidone-iodine to prevent postprostatectomy wound infection.

Design:

Patients with an indwelling catheter and scheduled for prostatectomy were divided into two groups. In patients in group 1 (n = 76) the indwelling catheter was simply removed without bladder irrigation. Patients in group 2 (n = 80) had their bladder washed with a nondiluted solution of povidone-iodine before surgery.

Patients:

One hundred fifty-six consecutive patients with an indwelling catheter and bacteriuria. Mean age was 64 years. All patients had an open prostatectomy during the 12-month study period. Patients undergoing open prostatectomy during the first 6 months of the study had no bladder irrigation and served as the control group. Patients undergoing open prostatectomy during the following 6 months had a bladder instillation with povidone-iodine.

Results:

Wound infection appeared in 17 of 76 patients (22.4%) without bladder washing and in 4 of 80 patients (5%) when 50 to 60 ml of the solution was retained in the bladder for 10 to 13 minutes (p=.001). The incidence of postoperative bacteriuria remained unchanged in the control group (100%) but was reduced to 22.5% in the treated group (p= .001). Statistical comparisons of incidence were done using the chi square test.

Conclusions:

It has been demonstrated that the use of preoperative bladder instillation of povidone-iodine may be highly effective in the prevention of postprostatectomy wound infection and in reducing the incidence of bacteriuria in patients with an indwelling catheter and urine colonization.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 12 , Issue 10 , October 1991 , pp. 579 - 582
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1991

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References

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