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The Risks of Transmission of the HTLV-III and Hepatitis B Virus in the Hospital

Published online by Cambridge University Press:  02 January 2015

David Shanson
David Shanson*
Affiliation:
Department of Medical Microbiology, Charing Cross and Westminster Medical School, London, England
*
Department of Clinical Microbiology, The Division of Pathology, St. Stephen's Hospital, Chelsea, SW10 9TH, England
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Extract

In the hospital, both HTLV-III and hepatitis B virus are most likely to spread via infected blood or contaminated blood products. A summary of the main factors affecting spread of these viruses and some observations made at the author's hospital in central London, will be discussed here.

AIDS was first recognized in Britain in 1981 and up to August 1985 there were 206 confirmed cases of AIDS with 114 deaths. The majority of patients with AIDS have been male homosexuals and less than 15% of the cases occurred outside of London. By August 1985 over 10,000 cases of AIDS had been reported in the US and it is clear by comparison that the current epidemic in Britain is in its early stages. Only a minority of London homosexuals have been infected. It is possible that an aggressive public health campaign could slow the course of the epidemic. Measures needed would include an increase in education, publicity, facilities for HTLV-III antibody tests, trained social workers and counseling on a massive scale. In the meantime the number of hospitalized patients with known HTLV-III infections has increased considerably during the last 2 years in certain hospitals in London (Figure 1). Approximately 33% of homosexuals attending sexually transmitted diseases (STD) clinics in London have serological evidence of HTLV-III infection. A few hospitals in central London have seen most of the patients with known HTLV-III or hepatitis B infections mainly because of the concentrations of homosexuals, drug addicts or other “risk groups” in the local catchment areas of these hospitals. A small number of hospitals in London and elsewhere in Britain have special hemophiliac centers and currently these centers have generally noted that more than 50% of their hemophiliac patients already have serological evidence of HTLV-III infection. Recent reports have documented the rate of increase of HTLV-III infections in British hemophiliac patients. During the last few years in London less than 10% of male homosexuals known to have HTLV-III infection and less than 1% of infected hemophiliac patients have developed AIDS.

Type
Research Article
Information
Infection Control & Hospital Epidemiology , Volume 7 , supplement S2: Proceedings of the Second ICI/Stuart Workshop , February 1986 , pp. 128 - 132
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1986

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References

1.Communicable Disease Surveillance Centre, Colindale: Surveillance on AIDS, Communicable Disease Report, August 1985.Google Scholar
2.Mortimer, PP, Jesson, WJ, Vandervelde, EM, et al: Prevalence of antibody to human T lymphotropic virus type III by risk group and area, United Kingdom 1978-1984. Br Med J 1985; 290:1176–1178.Google Scholar
3.Kitchen, LW, Barin, F, Sullivan, JL, et al: Aetiology of AIDS antibodies to HTLV III in haemophiliacs. Nature 1984; 312:367–369.Google Scholar
4.Barbara, JAA, Harrison, PJ, Howell, DH, et al: A sensitive single reverse passive haemagglutination test for detecting both HBsAg and anti-HBs. J Clin Pathol 1979; 32:1180–1183.Google Scholar
5.Cheingsong Popov, R, Weiss, RA, Dalgleish, A, et al: Prevalence of antibody to the human T-lymphotropic virus type III in AIDS and AIDS-risk patients in Britain. Lancet 1984; ii:477–480.Google Scholar
6.Grist, NR, Emslie, JAN: Infections in British clinical laboratories. J Clin Pathol 1985; 38:721–725.Google Scholar
7.Shanson, DC: Hepatitis B outbreak in operating theatre and intensive care staff. Lancet 1980; ii:596.Google Scholar
8. Editorial: Needlestick transmission of HTLV III from a patient infected in Africa. Lancet 1984; ii: 1376–1377.Google Scholar
9. Health Services Advisory Commission: Safety in health service laboratories; Hepatitis B, 1985 (HMSO, London).Google Scholar
10.Advisory Committee on Dangerous Pathogens: Acquired Immune Deficiency Syndrome—Interim Guidelines, 1984.Google Scholar
11.Ayliffe, G, Jeffries, D, Geddes, A, et al: AIDS and the health professions. Br Med J 1985; 290:853.Google Scholar
12.Shanson, DC: Nosocomial acquired immunodeficiency syndrome and human T-cell leukaemia lymphoma virus associated disease. J Hosp Infect 1984; 5:3–6.Google Scholar
13.Recommendations of a working party of the Hospital Infection Society on Acquired Immune Deficiency Syndrome: Supplement on AIDS of J Hosp Infect 1985, 6(suppl c).Google Scholar
14.Centers for Disease Control, Atlanta: Acquired Immune Deficiency Syndrome: Precautions for clinical and laboratory staffs. MMWR 1982; 31:577–580.Google Scholar
15.Rhame, FS: Prevention of in-hospital transmission of the acquired immune deficiency syndrome virus (HTLV-III: Current USA policy). J Hosp Infect 1985; 6(suppl c).Google Scholar