Hostname: page-component-76fb5796d-wq484 Total loading time: 0 Render date: 2024-04-26T07:52:08.982Z Has data issue: false hasContentIssue false
  • English
  • Français

Respiratory Fluoroquinolone Use and Influenza

Published online by Cambridge University Press:  02 January 2015

Philip M. Polgreen ,
Ming Yang ,
Ramanan Laxminarayan  and
Joseph E. Cavanaugh
Philip M. Polgreen*
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, and Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa
Ming Yang
Affiliation:
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa
Ramanan Laxminarayan
Affiliation:
Center for Disease Dynamics, Economics, and Policy, Washington DC; Princeton University, Princeton, New Jersey; and Public Health Foundation of India, New Delhi
Joseph E. Cavanaugh
Affiliation:
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa
*
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242 (philip-polgreen@uiowa.edu)
Get access Rights & Permissions [Opens in a new window]

Extract

We show that respiratory fluoroquinolone use is extremely seasonal and that fluoroquinolone use is strongly associated with influenza. In our time series model, instantaneous influenza activity was a significant predictor of use (P< .0001). Also, we estimated that reducing influenza activity by 20% would reduce prescriptions by 8%.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 7 , July 2011 , pp. 706 - 709
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Centers for Disease Control and Prevention. Get smart: know when antibiotics work. http://www.cdc.gov/getsmart/campaign-materials/about-campaign.html. Accessed February 4, 2010.Google Scholar
2.Grijalva, CG, Nuorti, JP, Griffin, MR. Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings. JAMA 2009;302:758–766.Google Scholar
3.Vanderweil, SG, Pelletier, AJ, Hamedani, AG, Gonzales, R, Metlay, JP, Camargo, CA Jr., Declining antibiotic prescriptions for upper respiratory infections, 1993–2004. Acad Emerg Med 2007;14:366–369.Google Scholar
4.Linder, JA, Huang, ES, Steinman, MA, Gonzales, R, Stafford, RS. Fluoroquinolone prescribing in the United States: 1995 to 2002. Am J Med 2005;118:259–268.Google Scholar
5.Centers for Disease Control and Prevention. Seasonal influenza (flu). http://www.cdc.gov/flu/. Accessed January 27, 2010.Google Scholar
6.Little, RJA, Rubin, DB. Statistical analysis with missing data. 2nd ed. Hoboken, NJ: Wiley, 2002:20.Google Scholar
7.Cryer, JD, Chan, KS. Time series analysis with applications in R. 2nd ed. New York: Springer, 2008:265–273.Google Scholar
8.Low, D. Reducing antibiotic use in influenza: challenges and rewards. Clin Microbiol Infect 2008;14:298–306.Google Scholar
9.Meier, CR, Napalkov, PN, Wegmuller, Y, Jefferson, T, Jick, H. Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom. Eur J Clin Microbiol Infect Dis 2000;19:834–842.Google Scholar
10.Neuzil, KM, Mellen, BG, Wright, PF, Mitchel, EF Jr, Griffin, MR. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med 2000;342:225–231.Google Scholar
11.Abella, S, Chapmana, S, Nadina, L, Warren, R. Seasonal variation in fluoroquinolone prescribing. J Antimicrob Chemother 1999;43:315–316.Google Scholar
12.Ganestam, F, Lundborg, CS, Grabowska, K, Cars, O, Linde, A. Weekly antibiotic prescribing and influenza activity in Sweden: a study throughout five influenza seasons. Scand J Infect Dis 2003;35:836–842.Google Scholar
13.Elseviers, MM, Ferech, M, Vander Stichele, RH, Goossens, H; and the ESAC Project Group. Antibiotic use in ambulatory care in Europe (ESAC data 1997–2002): trends, regional differences and seasonal fluctuations. Pharmacoepidemiol Drug Safety 2007;16:115–123.Google Scholar
14.Assink, MD, Kiewiet, JP, Rozenbaum, MH, et al. Excess drug prescriptions during influenza and RSV seasons in the Netherlands: potential implications for extended influenza vaccination. Vaccine 2009;27:1119–1126.Google Scholar
15.Glass, SK, Pearl, DL, McEwen, SA, Finley, R. A province-level risk factor analysis of fluoroquinolone consumption patterns in Canada (2000–06). J Antimicrob Chemother 2010;65:2019–2027.Google Scholar
16.Fleming, DM, Ross, AM, Cross, KW, Kendall, H. The reducing incidence of respiratory tract infection and its relation to antibiotic prescribing. Br J Gen Pract 2003;53:778–783.Google ScholarPubMed
17.Kwong, JC, Maaten, S, Upshur, RE, Patrick, DM, Marra, F. The effect of universal influenza immunization on antibiotic prescriptions: an ecological study. Clin Infect Dis 2009;49:750–756.Google Scholar
18.Falsey, AR, Murata, Y, Walsh, EE. Impact of rapid diagnosis on management of adults hospitalized with influenza. Arch Intern Med 2007;167:354–360.Google Scholar
19.Agency for Healthcare Research and Quality. Overview of the Nationwide Inpatient Sample (NIS). http://www.hcup-us.ahrq.gov/nisoverview.jsp. Accessed February 17, 2009.Google Scholar