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Postexposure Prophylaxis for Human Immunodeficiency Virus: Frequency of Initiation and Completion of Newly Recommended Regimen

Published online by Cambridge University Press:  02 January 2015

Kent A. Sepkowitz*
Affiliation:
St Clare's Hospital, New York City, New York Memorial Sloan-Kettering Cancer Center, New York City, New York
Pedro Rivera
Affiliation:
St Clare's Hospital, New York City, New York
Joyce Louther
Affiliation:
St Clare's Hospital, New York City, New York
Suzanne Lim
Affiliation:
Memorial Sloan-Kettering Cancer Center, New York City, New York
Betty Pryor
Affiliation:
New York Hospital-Cornell Medical Center, New York City, New York
*
Clinical Affairs, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Box 288, New York, NY 10021

Abstract

Recent evidence demonstrating the efficacy of zidovudine, as well as experience with protease inhibitors, led to revision of recommendations for occupational exposures to human immunodeficiency virus-infected blood. At our hospital, this resulted in significant increases in rates of reported exposures and prophylaxis initiation. Among 10 healthcare workers given three-drug, protease-inhibitor-containing regimens, five completed 4 weeks, two completed 4 weeks of two drugs, and three stopped due to intolerance. Three workers missed work due to side effects

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1998

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