The primary objectives of nurses caring for the immunosuppressed patient are to create a safe, peaceful environment and to promote the quality of the patient's life. Strengthening the patient's defense mechanisms is inherent in these nursing objectives, and the nurse must have certain competencies to reinforce these defense mechanisms. One competency is a thorough understanding of the immunosuppressed patient. The infection control practitioner (ICP) should assist the nurse in understanding what an immunosuppressed patient is, what his risk of infection is, what his reaction to infection might be, and what isolation practices are appropriate. Another necessary nursing skill is proficiency in patient assessment, not only when the patient is admitted, but on a continuous basis since the patient's status can change so rapidly.

Finally the nurse must have the ability to implement appropriate nursing measures. The nurse must use the principles of asepsis in all patient care activities, recognize risk factors of infection, and understand the importance of such details as proper nutrition, oral hygiene, and skin care. Psychological support is also an essential part of the nursing care plan.

Nursing care affects the well-being of the immunosuppressed patient and infection control practitioners have a role in ascertaining that nurses know how to treat such patients appropriately.