Hostname: page-component-76fb5796d-zzh7m Total loading time: 0 Render date: 2024-04-26T13:23:24.947Z Has data issue: false hasContentIssue false
  • English
  • Français

Mupirocin Resistance in Clinical Isolates of Staphylococcus aureus

Published online by Cambridge University Press:  02 January 2015

Paula G. Jones ,
Terri Sura ,
Michael Harris  and
Anne Strother
Paula G. Jones*
Affiliation:
Department of Medicine and the Department of Microbiology, University of Wisconsin–Milwaukee Clinical Campus, Aurora Consolidated Laboratories, Milwaukee, Wisconsin
Terri Sura
Affiliation:
Department of Medicine and the Department of Microbiology, University of Wisconsin–Milwaukee Clinical Campus, Aurora Consolidated Laboratories, Milwaukee, Wisconsin
Michael Harris
Affiliation:
Department of Medicine and the Department of Microbiology, University of Wisconsin–Milwaukee Clinical Campus, Aurora Consolidated Laboratories, Milwaukee, Wisconsin
Anne Strother
Affiliation:
Department of Medicine and the Department of Microbiology, University of Wisconsin–Milwaukee Clinical Campus, Aurora Consolidated Laboratories, Milwaukee, Wisconsin
*
University of Wisconsin–Milwaukee Clinical Campus, Aurora Sinai Medical Center, 945 N. 12th Street, Milwaukee, WI53201-0342
Get access Rights & Permissions [Opens in a new window]

Abstract

One hundred isolates of Staphylococcus aureus were collected in a laboratory serving several hospitals and clinics in southeastern Wisconsin and tested for mupirocin susceptibility. Only two isolates of S. aureus showed mupirocin resistance. The mupirocin-resistant isolates were from hospitalized patients with positive blood cultures.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 4 , April 2003 , pp. 300 - 301
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Kauffman, CA, Terpenning, MS, He, X, et al. Attempts to eradicate methicillin-resistant Staphylococcus aureus from a long-term facility with the use of mupirocin ointment. Am J Med 1993;94:371–378.Google Scholar
2.Harbarth, S, Dharan, S, Liassine, N, Herrault, P, Auckenthaler, R, Pittet, D. Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 1999;43:1412–1416.Google Scholar
3.Morton, TM, Johnston, JL, Patterson, J, Archer, GL. Characterization of a conjugative staphylococcal mupirocin resistance plasmid. Antimicrob Agents Chemother 1995;39:1272–1280.Google Scholar
4.Bradley, SF, Ramsey, MA, Morton, TM, Kauffman, CA. Mupirocin resistance: clinical and molecular epidemiology. Infect Control Hosp Epidemiol 1995;16:354–358.CrossRefGoogle ScholarPubMed
5.Henkel, T, Finlay, J. Emergence of resistance during mupirocin treatment: is it a problem in clinical practice? J Chemother 1999;11:331–337.Google Scholar
6.Semret, M, Miller, MA. Topical mupirocin for eradication of MRSA colonization with mupirocin-resistant strains. Infect Control Hosp Epidemiol 2001;22:578–580.Google Scholar
7.National Committee for Clinical Laboratory Standards. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Wayne, PA: National Committee for Clinical Laboratory Standards; 1998. Document M100-S8.Google Scholar
8.Finlay, JE, Miller, LA, Poupard, JA. Interpretive criteria for testing susceptibility of staphylococci to mupirocin. Antimicrob Agents Chemother 1997;41:1137–1139.Google Scholar
9.Perez-Fontan, M, Rosales, M, Rodriguez-Carmona, A, Falcon, TG, Valdes, F. Mupirocin resistance after long-term use for Staphylococcus aureus colonization in patients undergoing chronic peritoneal dialysis. Am J Kidney Dis 2002;39:337–341.Google Scholar
10.Annigeri, R, Conly, J, Vas, S, et al. Emergence of mupirocin-resistant Staphylococcus aureus in chronic peritoneal dialysis patients using mupirocin prophylaxis to prevent exit-site infection. Pent Dial Int 2001;21:554–559.Google Scholar