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Morbidity and Mortality Associated with Multiple Episodes of Nosocomial Bloodstream Infection: A Cohort Study

Published online by Cambridge University Press:  21 June 2016

Patti J. Miller  and
Barry M. Farr
Patti J. Miller*
Affiliation:
Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
Barry M. Farr
Affiliation:
University of Virginia's, State-wide Infection Control Program, Charlottesville, Virginia
*
Research Administrator, Box 173—Department of Medicine, University of Virginia, Charlottesville, VA 22908
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Abstract

A retrospective cohort study of patients with multiple nosocomial bloodstream infections (BSIs) compared with patients suffering only one BSI was conducted to assess morbidity and mortality. Three hundred forty-one patients with BSIs were identified, including 33 with multiple BSIs (9.7%). No significant differences existed between patients experiencing one BSI compared to those experiencing multiple BSIs in age, sex, race, severity of underlying disease, hypothermia, hypoxemia, oliguria, metabolic acidosis, or hypotension. Sixteen of 33 (49%) with multiple BSIs died compared with 124 of 308 (40%) with only one BSI (P =0.36), leading to a relative risk of 1.23 for death and an attributable mortality of 9% in those with multiple BSIs.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 10 , Issue 5 , May 1989 , pp. 216 - 219
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1989

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