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Impact of removing ESBL designation from culture reports on the selection of antibiotics for the treatment of infections associated with ESBL-producing organisms

Published online by Cambridge University Press:  06 April 2020

Mark D. Lesher Open the ORCID record for Mark D. Lesher [Opens in a new window] ,
Cory M. Hale ,
Dona S. S. Wijetunge ,
Matt R. England ,
Debra S. Myers  and
David W. Craft
Mark D. Lesher*
Affiliation:
Department of Pharmacy, Milton S. Hershey Medical Center, Hershey, Pennsylvania
Cory M. Hale*
Affiliation:
Department of Pharmacy, Milton S. Hershey Medical Center, Hershey, Pennsylvania
Dona S. S. Wijetunge
Affiliation:
Pathology and Laboratory Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania
Matt R. England
Affiliation:
Pathology and Laboratory Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania
Debra S. Myers
Affiliation:
Pathology and Laboratory Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania
David W. Craft
Affiliation:
Pathology and Laboratory Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania
*
Author for correspondence: Mark Lesher, E-mail: mlesher1@pennstatehealth.psu.edu. Or Cory Hale, E-mail: chale@pennstatehealth.psu.edu
Author for correspondence: Mark Lesher, E-mail: mlesher1@pennstatehealth.psu.edu. Or Cory Hale, E-mail: chale@pennstatehealth.psu.edu
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Abstract

We characterized the impact of removal of the ESBL designation from microbiology reports on inpatient antibiotic prescribing. Definitive prescribing of carbapenems decreased from 48.4% to 16.1% (P = .01) and β-lactam–β-lactamase inhibitor combination increased from 19.4% to 61.3% (P = .002). Our findings confirm the importance of collaboration between microbiology and antimicrobial stewardship programs.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 41 , Issue 5 , May 2020 , pp. 604 - 607
Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved

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Footnotes

a

Present affiliations: Texas Children’s Hospital/Baylor College of Medicine, Houston, Texas [D.S.S.W] and Summa Health, Akron City Hospital, Akron, Ohio [M.E.])

PREVIOUS PRESENTATION: Some of these data were previously presented as a poster at the ASM Microbe 2018 conference on June 8, 2018, in Atlanta, Georgia.

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