Hostname: page-component-76fb5796d-dfsvx Total loading time: 0 Render date: 2024-04-28T09:51:43.297Z Has data issue: false hasContentIssue false

Evaluation of an antigen-test–based strategy to reduce duration of transmission-based precautions for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection in hospitalized patients

Published online by Cambridge University Press:  04 August 2023

Gregory M. Schrank*
Affiliation:
Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland
Michelle Harris-Williams
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Kelly Schiavone
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Martha C. Lusby
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Cindy Dove
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Surbhi Leekha
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
*
Corresponding author: Gregory Schrank; Email: gschrank@som.umaryland.edu

Abstract

An academic hospital implemented a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antigen-test–based strategy to facilitate discontinuation of precautions for patients admitted with a positive SARS-CoV-2 test. Of 171 patients that underwent antigen testing, 68% had an initial negative test performed a median of 5 days after admission. Antigen testing reduced isolation time by 144 hours.

Type
Concise Communication
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Interim Infection Prevention and Control Recommendations for Healthcare Personnel During the Coronavirus Disease 2019 (COVID-19) Pandemic. Centers for Disease Control and Prevention website. https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-control-recommendations.html. Published 2022. Accessed January 12, 2023.Google Scholar
O’Reilly, GM, Mitchell, RD, Mitra, B, et al. Impact of patient isolation on emergency department length of stay: a retrospective cohort study using the Registry for Emergency Care. Emerg Med Australas 2020;32:10341039.CrossRefGoogle ScholarPubMed
Talbot, TR, Hayden, MK, Yokoe, DS, et al. Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: challenges and considerations. Infect Control Hosp Epidemiol 2023;44:27.CrossRefGoogle ScholarPubMed
Alsuhaibani, MA, Kobayashi, T, Trannel, A, et al. Coronavirus disease 2019 (COVID-19) admission screening and assessment of infectiousness at an academic medical center in Iowa, 2020. Infect Control Hosp Epidemiol 2022;43:974978.CrossRefGoogle ScholarPubMed
Korenkov, M, Poopalasingam, N, Madler, M, et al. Evaluation of a rapid antigen test to detect SARS-CoV-2 infection and identify potentially infectious individuals. J Clin Microbiol 2021;59:e0089621.CrossRefGoogle ScholarPubMed
Puhach, O, Meyer, B, Eckerle, I. SARS-CoV-2 viral load and shedding kinetics. Nat Rev Microbiol 2023;21:147161.Google ScholarPubMed
Kirby, JE, Riedel, S, Dutta, S, et al. SARS-CoV-2 antigen tests predict infectivity based on viral culture: comparison of antigen, PCR viral load, and viral culture testing on a large sample cohort. Clin Microbiol Infect 2023;29:94100.CrossRefGoogle ScholarPubMed
In vitro diagnostics EUAs—antigen diagnostic tests for SARS-CoV-2. US Food and Drug Administration website. https://www.fda.gov/medical-devices/coronavirus-disease-2019-covid-19-emergency-use-authorizations-medical-devices/in-vitro-diagnostics-euas-antigen-diagnostic-tests-sars-cov-2#SerialTesting. Published 2022. Accessed February 1, 2023.Google Scholar
Supplementary material: File

Schrank et al. supplementary material

Schrank et al. supplementary material 1

Download Schrank et al. supplementary material(File)
File 441 KB
Supplementary material: File

Schrank et al. supplementary material

Schrank et al. supplementary material 2

Download Schrank et al. supplementary material(File)
File 440.1 KB