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Emerging Infectious Diseases in the Institutional Setting: Another Hot Zone

Published online by Cambridge University Press:  02 January 2015

Stephen M. Ostroff*
Affiliation:
Centers for Disease Control and Prevention, Atlanta, GA
*
National Center for Infectious Diseases, Mailstop C12, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333

Abstract

During the closing years of the 20th century, there has been an unprecedented number of newly recognized infectious agents and a resurgence of infectious diseases only recently thought to be conquered. These problems have been compounded by the increasing number of pathogens that have evolved resistance to antimicrobial agents. Hospitals and other institutional settings occupy a pivotal niche in the emergence of infectious agents due to factors such as the large concentrations of ill and immunocompromised persons, evolving technologies in healthcare settings, routine breeches of host defense mechanisms, and frequent use of antimicrobial agents. Any comprehensive strategy to address emerging infectious diseases must incorporate provisions for healthcare settings, including efforts to enhance surveillance, response capacity, training, education, applied research, and routine implementation of prevention measures.

Type
From the Fourth International Conference on the Prevention of Infection
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1996

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References

1. Nichol, ST, Spiropoulou, CF, Morzunov, S, et al. Genetic identification of a Hantavirus associated with an outbreak of acute respiratory disease. Science 1993;262:914917.Google Scholar
2. Centers for Disease Control and Prevention. Update: human plague–India, 1994. MMWR 1994;43:722723.Google Scholar
3. Muyembe, T, Kipasa, M, International Scientific and Technical Committee and WHO Collaborating Centre for Haemorrhagic Fevers. Ebola haemorrhagic fever in Kikwit, Zaire. Lancet 1995;345:1448. Letter.CrossRefGoogle ScholarPubMed
4. Will, RG, Ironside, JW, Zeidler, M, et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 1996;347:921925.CrossRefGoogle ScholarPubMed
5. Preston, R. The Hot Zone. New York, NY: Random House; 1994.Google Scholar
6. Garrett, L. The Coming Plague: Newly Emerging Diseases in a World Out of Balance. New York, NY: Farrar, Straus, and Giroux; 1994.Google Scholar
7. Institute of Medicine. In: Lederberg, J, Shope, RE, Oaks, SC Jr, eds. Emerging Infections: Microbial Threats to Health in the United States. Washington, DC: National Academy Press; 1992.Google Scholar
8. Kilmarx, PH, Ksiazek, TG, Zaki, SR, et al. Outbreak of Ebola hemorrhagic fever-Zaire, 1995: surveillance report. In: 45th Annual Epidemic Intelligence Service (EIS) Conference; April 1996; Atlanta, GA. Abstract.Google Scholar
9. Dowell, SF. Ebola hemorrhagic fever: why were children spared? Pediatr Infect Dis J 1996;15:189191.CrossRefGoogle ScholarPubMed
10. WHO/International Study Team. Ebola haemorrhagic fever in Sudan, 1976. Bull World Health Organ 1978;56:247270.Google Scholar
11. International Commission. Ebola haemorrhagic fever in Zaire, 1976. Bull World Health Organ 1978;56:271293.Google Scholar
12. Fisher-Hoch, SP, Tomori, O, Nasidi, A, et al. Review of cases of nosocomial Lassa fever in Nigeria: the high price of poor medical practice. Br Med J 1995;311:857859.CrossRefGoogle Scholar
13. Dooley, SW, Villarino, ME, Lawrence, M, et al. Nosocomial transmission of tuberculosis in a hospital unit for HIV-infected patients. JAMA 1992;267:26322635.Google Scholar
14. Edlin, BR, Tokars, JI, Grieco, MH, et al. An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome. N Engl J Med 1992;326:15141521.CrossRefGoogle ScholarPubMed
15. Beck-Sague, C, Dooley, SW, Hutton, MD, et al. Hospital outbreak of multidrug-resistant Mycobacterium tuberculosis infections: factors in transmission to staff and HIV-infected patients. JAMA 1992;268:12801286.CrossRefGoogle ScholarPubMed
16. Pearson, ML, Jereb, JA, Frieden, TR, et al. Nosocomial transmission of multidrug-resistant Mycobacterium tuberculosis: a risk to patients and healthcare workers. Ann Intern Med 1992;117:191196.CrossRefGoogle Scholar
17. Coronado, VG, Beck-Sague, CM, Hutton, MD, et al. Transmission of multidrug-resistant Mycobacterium tuberculosis among persons with human immunodeficiency virus infection in an urban hospital: epidemiologic and restriction fragment length polymorphism analysis. J Infect Dis 1993;168:10521055.CrossRefGoogle Scholar
18. Shafer, RW, Edlin, BR. Tuberculosis in patients infected with human immunodeficiency virus: perspective on the past decade. Clin Infect Dis 1996;22:683704.CrossRefGoogle ScholarPubMed
19. Valway, SE, Greifinger, RB, Papania, M, et al. Multidrug-resistant tuberculosis in the New York State prison system, 1990-1991. J Infect Dis 1994;170:151156.Google Scholar
20. Hopewell, PC. Impact of human immunodeficiency virus infection on the epidemiology, clinical features, management, and control of tuberculosis. Clin Infect Dis 1992;15:540547.CrossRefGoogle ScholarPubMed
21. Centers for Disease Control and Prevention. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care facilities, 1994. MMWR 1994;43(suppl RR-13):1132.Google Scholar
22. Allander, T, Medin, C, Kacobson, SH, Grillner, L, Persson, MAA. Hepatitis C transmission in a hemodialysis unit: molecular evidence for spread of virus among patients not sharing equipment. J Med Virol 1994;43:415419.Google Scholar
23. Calabrese, G, Vagelli, G, Gonella, M. Patient-to-patient transmission of hepatitis C virus. Lancet 1995;345:1443. Letter.Google ScholarPubMed
24. Allander, T, Gruber, A, Naghavi, M, et al. Frequent patient-to-patient transmission of hepatitis C virus in a haematology ward. Lancet 1995;345:603607.Google Scholar
25. Centers for Disease Control and Prevention. Outbreak of hepatitis C associated with intravenous immunoglobulin administration. MMWR 1994;43:505509.Google Scholar
26. Colombo, M, Mannucci, PM, Carnelli, V, et al. Transmission of non-A, non-B hepatitis by heat-treated factor VIII concentrate. Lancet 1985;ii:14.CrossRefGoogle Scholar
27. Holmes, GP, McCormick, JB, Trock, SC, et al. Lassa fever in the United States: investigation of a case and new guidelines for management. N Engl J Med 1990;323:11201123.CrossRefGoogle ScholarPubMed
28. LeGuenno, B, Formenty, P, Wyers, M, Gounon, P, Walker, F, Boesch, C. Isolation and partial characterization of a new strain of Ebola virus. Lancet 1995;345:12711274.Google Scholar
29. Centers for Disease Control and Prevention. Imported cholera associated with a newly described toxigenic Vibrio cholerae O139 strain-California, 1993. MMWR 1993;42:501503.Google Scholar
30. Dalsgaard, A, Nielsen, GL, Echeverria, P, Larsen, JL, Schonheyder, HC. Vibrio cholerae O139 in Denmark. Lancet 1995;345:16371638. Letter.Google Scholar
31. Centers for Disease Control and Prevention. Detection of notifiable diseases through surveillance for imported plague- New York, 1994. MMWR 1994;43:805807.Google Scholar
32. Stout, JE, Yu, VL, Vickers, RM, et al. Ubiquitousness of Legionella pneumophila in the water supply of a hospital with endemic Legionnaires' disease. N Engl J Med 1982;306:466468.Google Scholar
33. Hanrahan, JP, Morse, DL, Scharf, VB, et al. A community hospital outbreak of legionellosis; transmission by potable hot water. Am J Epidemiol 1987;125:639649.CrossRefGoogle ScholarPubMed
34. Struelens, MJ, Maes, N, Rost, F, et al. Genotypic and phenotypic methods for the investigation of a nosocomial Legionella pneumophila outbreak and efficacy of control measures. J Infect Dis 1992;166:2230.Google Scholar
35. O'Mahoney, MC, Stanwell-Smith, RE, Tillett, HE, et al. The Stafford outbreak of Legionnaires' disease. Epidemiol Infect 1990;104:361380.Google Scholar
36. Zuravleff, JJ, Yu, VL, Shonnard, JW, Rihs, JD, Best, M. Legionella pneumophila contamination of a hospital humidifier-demonstration of aerosol transmission and subsequent subclinical infection in exposed guinea pigs. Am Rev Respir Dis 1983;128:657661.Google Scholar
37. Kaufman, A, McDade, J, Patton, C, et al. Pontiac fever: isolation of the etiologic agent (Legionella pneumophila) and demonstration of its mode of transmission. Am J Epidemiol 1981;114:337347.Google Scholar
38. Mastro, TD, Fields, BS, Breiman, RF, et al. Nosocomial Legionnaires’ disease and use of medication nebulizers. J Infect Dis 1991;163:667671.CrossRefGoogle ScholarPubMed
39. Woo, AH, Goetz, A, Yu, VL. Transmission of Legionella by respiratory equipment aerosol generating devices. Chest 1992;102:15861590.Google Scholar
40. Lowry, PW, Blankenship, RJ, Gridley, W, Troup, NJ, Tompkins, LS. A cluster of legionella sternal-wound infections due to postoperative topical exposure to contaminated tap water. N Engl J Med 1991;324:109113.CrossRefGoogle ScholarPubMed
41. Horbach, I, Fehrenbach, FJ. Legionellosis in heart transplant recipients. Infection 1990;18:361363.Google Scholar
42. Dowling, JN, Pasculle, AW, Frola, FN, Zaphyr, MK, Yee, RB. Infections caused by Legionella micdadei and Legionella pneu-mophila among renal transplant recipients. J Infect Dis 1984;149:703713.Google Scholar
43. Kugler, JW, Armitage, JO, Helms, CM, et al. Nosocomial Legionnaires' disease: occurrence in recipients of bone marrow transplants. Am J Med 1983;74:281288.CrossRefGoogle ScholarPubMed
44. Vitek, CR, Breiman, RF, Ksaizek, TG, et al. Evidence against person-to-person transmission of Hantavirus to health care workers. Clin Infect Dis 1996;22:824826.Google Scholar
45. Karmali, MA, Arbus, GS, Petric, M, Patrick, ML, Roscoe, M, Shaw, J. Hospital-acquired Escherichia coli O157:H7 associated haemolytic uraemic syndrome in a nurse. Lancet 1988;i:526. Letter.Google Scholar
46. Centers for Disease Control and Prevention. Human rabies- Texas and California, 1993. MMWR 1994;43:9396.Google Scholar
47. Centers for Disease Control and Prevention. Human rabies- New York, 1993. MMWR 1993:799, 805806.Google Scholar
48. Centers for Disease Control and Prevention. Human rabies- California, 1994. MMWR 1994;43:455457.Google Scholar
49. Centers for Disease Control and Prevention. Human rabies- Miami, 1994. MMWR 1994;43:773775.Google Scholar
50. Centers for Disease Control and Prevention. Human rabies- West Virginia, 1994. MMWR 1995;44:8687, 93.Google Scholar
51. Centers for Disease Control and Prevention. Human rabies-Alabama, Tennessee, and Texas, 1994. MMWR 1995;44:269272.Google Scholar
52. Centers for Disease Control and Prevention. Human rabies- Washington, 1995. MMWR 1995;44:625627.Google Scholar
53. Centers for Disease Control and Prevention. Human rabies- Connecticut, 1995. MMWR 1996;45:207209.Google Scholar
54. Centers for Disease Control and Prevention. Human rabies- California, 1995. MMWR 1996;45:353356.Google Scholar
55. Moellering, RC Jr. The Garrod lecture: the Enterococcus: a classic example of the impact of antimicrobial resistance on therapeutic options. J Antimicrob Chemother 1991;28:112.Google Scholar
56. Frieden, TR, Munsiff, SS, Low, DE, et al. Emergence of van-comycin-resistant enterococci in New York City. Lancet 1993;342:7679.Google Scholar
57. Cohen, ML. Epidemiology of drug resistance: implications for a post-antimicrobial era. Science 1992;257:10501055.Google Scholar
58. Hospital Infection Control Practices Advisory Committee. Recommendations for preventing the spread of vancomycin resistance. MMWR 1995;44(RR-12):113.Google Scholar
59. Jernigan, DB, Hofmann, J, Cetron, MS, et al. Outbreak of Legionnaires' disease among cruise ship passengers exposed to a contaminated whirlpool spa. Lancet 1996;347:494499.Google Scholar
60. Duchin, JS, Koster, F, Peters, CJ, et al. Hantavirus pulmonary syndrome: clinical description of seventeen patients with a newly recognized disease. N Engl J Med 1994;330:949955.Google Scholar
61. Bell, BP, Goldoft, M, Griffin, PM, et al. A multistate outbreak of Escherichia coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers: the Washington experience. JAMA 1994;272:13491353.Google Scholar
62. Boyce, TG, Pemberton, AG, Wells, JG, Griffin, PM. Screening for Escherichia coli 0157:H7-a nationwide survey of clinical laboratories. J Clin Microbiol 1995;33:32753277.Google Scholar
63. Tenover, FC, Tokars, J, Swenson, J, Paul, S, Spitalny, K, Jarvis, W. Ability of clinical laboratories to detect antimicrobial agent-resistant enterococci. J Clin Microbiol 1993;31:16951699.Google Scholar