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A Clostridium difficile Infection (CDI) Stewardship Initiative Improves Adherence to Practice Guidelines for Management of CDI

Published online by Cambridge University Press:  02 January 2015

Lucy A. Jury
Affiliation:
Geriatric Research, Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
Myreen Tomas
Affiliation:
Department of Infectious Diseases and HIV Medicine, University Hospitals Case Medical Center, Cleveland, Ohio
Sirisha Kundrapu
Affiliation:
Department of Infectious Diseases and HIV Medicine, University Hospitals Case Medical Center, Cleveland, Ohio
Brett Sitzlar
Affiliation:
Geriatric Research, Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
Curtis J. Donskey*
Affiliation:
Geriatric Research, Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
*
Geriatric Research, Education, and Clinical Center, Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, OH 44106 (curtisdl23@yahoo.com)

Abstract

A Clostridium difficile infection (CDI) stewardship initiative reduced inappropriate prescription of empirical CDI therapy and improved timeliness of treatment and adherence to clinical practice guidelines for management of CDI. The initiative required minimal resources and could easily be incorporated into traditional antimicrobial stewardship programs.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

1.Le, F, Arora, V, Shah, DN, Salazar, M, Palmer, HR, Garey, KW. A real-world evaluation of oral vancomycin for severe Clostridium difficile infection: implications for antibiotic stewardship programs. Pharmacotherapy 2012;32:129134.Google Scholar
2.Byker, GL, Dinh, MT, Gunaratnam, NT, Robinson, EA, Shehab, TM, Malani, AN. Management of Clostridium diffkile infection: survey of practices and compliance with national guidelines among primary care physicians Infect Control Hosp Epidemiol 2009;30:397399.Google Scholar
3.Vasa, CV, Glatt, AE. Effectiveness and appropriateness of empiric metronidazole for Clostridium difficile-associated diarrhea. Am J Gasroenterol 2003;98:354358.CrossRefGoogle ScholarPubMed
4.Saade, E, Deshpande, A, Kundrapu, S, et al. Appropriateness of empiric therapy in patients with suspected Clostridium difficile infection. Curr Med Res Opin 2013;29:985988.Google Scholar
5.Cohen, SH, Gerding, DN, Johnson, S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 2010;31:431455.Google Scholar
6.Guerrero, DM, Nerandzic, MM, Jury, LA, Chang, S, Jump, RL, Donskey, CJ. Clostridium difficile infection in a Department of Veterans Affairs long-term care facility. Infect Control Hosp Epidemiol 2011;32:513515.Google Scholar
7.Kundrapu, S, Jury, LA, Sitzlar, B, Sunkesula, VCK, Sethi, AK, Donskey, CJ. Easily modified factors contribute to delays in diagnosis of Clostridium difficile infection: a cohort study and intervention. J Clin Microbiol 2013;51:23652370.Google Scholar
8.Al-Nassir, WN, Sethi, AK, Li, Y, Pultz, MJ, Riggs, MM, Donskey, CJ. Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease Antimicrob Agents Chemother 2008;52:24032406.Google Scholar
9.Shaughnessy, MK, Amundson, WH, Kuskowski, MA, DeCarolis, DD, Johnson, JR, Drekonja, DM. Unnecessary antimicrobial use in patients with current or recent Clostridium difficile infection. Infect Control Hosp Epidemiol 2013;34:109116.Google Scholar