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Case-Control Study of Risk Factors for Mediastinitis After Cardiovascular Surgery

Published online by Cambridge University Press:  21 June 2016

M. J. López Gude
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
R. San Juan*
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
J. M. Aguado
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
L. Maroto
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
F. López-Medrano
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
J. M. Cortina Romero
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
J. J. Rufilanchas
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
*
Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Edificio Maternidad, planta 6°, Avenida de Andalucía km 5, 400, 28041 Madrid, Spain (rafasjg@yahoo.es)

Abstract

We report results of a case-control study in which we evaluated 41 risk factors potentially associated with the development of post-surgical mediastinitis. There were 163 case patients and 326 control patients. Independent risk factors kept in the final multivariate logistic regression model were obesity (defined as a body mass index of greater than 30), diabetes mellitus, chronic obstructive pulmonary disease, preoperative stay longer than 1 week, pulmonary hypertension, perioperative myocardial infarction, and reoperation.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

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References

1. Munoz, P, Menasalvas, A, Bernaldo de Quiros, JC, Desco, M, Vallejo, JL, Bouza, E. Postsurgical mediastinitis: a case-control study. Clin Infect Dis 1997; 25:10601064.CrossRefGoogle ScholarPubMed
2. Bitkover, CY, Gardlund, B. Mediastinitis after cardiovascular operations: a case-control study of risk factors. Ann Thorac Surg 1998; 65:3640.CrossRefGoogle ScholarPubMed
3. Abboud, CS, Wey, SB, Baltar, VT. Risk factors for mediastinitis after cardiac surgery. Ann Thorac Surg 2004; 77:676683.CrossRefGoogle ScholarPubMed
4. Garner, JS, Jarvis, WR, Emori, TG, Horan, TC, Hughes, JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988; 16:128140.Google Scholar
5. Russo, PL, Spelman, DW. A new surgical-site infection risk index using risk factors identified by multivariate analysis for patients undergoing coronary artery bypass graft surgery. Infect Control Hosp Epidemiol 2002; 23:372376.Google Scholar
6. Olsen, MA, Lock-Buckley, P, Hopkins, D, Polish, LB, Sundt, TM, Fraser, VJ. The risk factors for deep and superficial chest surgical-site infections after coronary artery bypass graft surgery are different. J Thorac Cardiovasc Surg 2002; 124:136145.CrossRefGoogle ScholarPubMed
7. Losanoff, JE, Richman, BW, Jones, JW. Risk analysis of deep sternal wound infection and mediastinitis in cardiac surgery. Thorac Cardiovasc Surg 2002; 50:385.CrossRefGoogle ScholarPubMed
8. Gummert, JF, Barten, MJ, Hans, C, et al. Mediastinitis and cardiac surgery—an updated risk factor analysis in 10,373 consecutive adult patients. Thorac Cardiovasc Surg 2002; 50:8791.CrossRefGoogle Scholar
9. Trick, WE, Scheckler, WE, Tokars, JI, et al. Modifiable risk factors associated with deep sternal site infection after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2000; 119:108114.Google Scholar
10. Ottino, G, De Paulis, R, Pansini, S, et al. Major sternal wound infection after open-heart surgery: a multivariate analysis of risk factors in 2,579 consecutive operative procedures. Ann Thorac Surg 1987; 44:173179.Google Scholar
11. Grossi, EA, Culliford, AT, Krieger, KH, et al. A survey of 77 major infectious complications of median sternotomy: a review of 7,949 consecutive operative procedures. Ann Thorac Surg 1985; 40:214223.Google Scholar