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Applying mucosal barrier injury laboratory-confirmed bloodstream infection criteria in patients with solid tumors and hematologic malignancies: A retrospective cohort study looking for the real source of infection

Published online by Cambridge University Press:  11 February 2022

Ana Carolina Puin da Silva*
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Michely Fernandes Vieira
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Maristela Pinheiro Freire
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Lumena Vaz
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Patrícia Rodrigues Bonazzi
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Karim Yaqub Ibrahim
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Maria Del Pilar Esteves Diz
Affiliation:
Oncology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Paulo Marcelo Hoff
Affiliation:
Oncology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Juliana Pereira
Affiliation:
Hematology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Vanderson Geraldo Rocha
Affiliation:
Hematology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil
Edson Abdala
Affiliation:
Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil Department of Infectious and Parasitic Diseases, School of Medicine, University of São Paulo, Brazil
*
Author for correspondence: A. C. P. Silva, E-mail: anacarolina_puin@yahoo.com

Abstract

We evaluated the interference of the mucosal barrier injury (MBI) laboratory-confirmed bloodstream infection (MBI-LCBI) criteria on the central-line–associated bloodstream infection (CLABSI) incidence density, and the proportion of catheter-related bloodstream infections (CRBSIs) among those classified as MBI. We detected 339 CLABSIs: 15.0% were classified as MBI-LCBIs, and among these, 19.6% were classified as CRBSIs.

Type
Concise Communication
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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