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Nosocomial Infections With Ceftazidime-Resistant Pseudomonas aeruginosa: Risk Factors and Outcome

Published online by Cambridge University Press:  02 January 2015

Sai-Cheong Lee*
Affiliation:
Division of Infectious Diseases, Chang GungMemorial Hospital, Keelung
Chang-Phone Fung
Affiliation:
Division of Infectious Diseases, Veterans General Hospital, Taipei
Peter Yuk-Fong Liu
Affiliation:
Department of Internal Medicine, Shalu Tung's Memorial Hospital, Chang Gung College of Medicine and Technology, Taiwan, Republic of China
Tzu-Chien Wang
Affiliation:
Department of Molecular and Cellular Biology, Chang Gung College of Medicine and Technology, Taiwan, Republic of China
Lai-Chu See
Affiliation:
Department of Public Health, Chang Gung College of Medicine and Technology, Taiwan, Republic of China
Ning Lee
Affiliation:
Department of Pathology, Chang GungMemorial Hospital, Keelung
Shu-Chu Chen
Affiliation:
Division of Infectious Diseases, Chang GungMemorial Hospital, Keelung
Wen-Bin Shieh
Affiliation:
Division of Infectious Diseases, Chang GungMemorial Hospital, Keelung
*
Division of Infectious Diseases, Chang Gung Memorial Hospital, 222 Mai Chin Rd, Keelung, Taiwan, Republic of China

Abstract

Prospective studies were conducted for nosocomial Pseudomonas aeruginosa infections from February 1, 1994, to October 30,1995. Of 97 P aeruginosa isolates from 97 patients, 35 were resistant to ceftazidime. Logistic regression revealed previous cephalosporin or piperacillin use as independent risk factors for nosocomial ceftazidime-resistant P aeruginosa infection. Pulsed-field gel electrophoresis revealed that four nosocomial ceftazidime-resistant P aeruginosa infections were caused by cross-infection, probably through medical personnel.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1999

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