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Increasing Incidence of Sterile-Site Infections Due to Non-Multidrug-Resistant, Oxacillin-Resistant Staphylococcus aureus Among Hospitalized Patients

Published online by Cambridge University Press:  02 January 2015

Garrett E. Schramm
Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, Missouri
Jennifer A. Johnson
Department of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri
Joshua A. Doherty
Medical Informatics, BJC Healthcare, St. Louis, Missouri
Scott T. Micek*
Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, Missouri
Marin H. Kollef
Department of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri
Barnes-Jewish Hospital, Department of Pharmacy, Mailstop 90-52-411, 216 S. Kingshighway Blvd., St. Louis, MO 63110 (


The incidence of community-associated, healthcare-associated, and hospital-acquired sterile-site infections due to methicillin-re-sistant Staphylococcus aureus (MRSA) isolates and the susceptibility of the isolates to non-β-lactam antibiotics were evaluated for 549 hospitalized patients during a 3-year period. The incidence of community-associated MRSA infection increased significantly. The annual percentage of MRSA isolates from cases of healthcare-associated and hospital-acquired infection that were susceptible to 3 or more non-β-lactam antibiotics increased significantly.

Concise Communication
Copyright © The Society for Healthcare Epidemiology of America 2007

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