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Hospital outbreak of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant in partially and fully vaccinated patients and healthcare workers in Toronto, Canada

Published online by Cambridge University Press:  28 October 2021

Erica K. Susky
Affiliation:
Infection Prevention and Control Department, University Health Network, Toronto, Ontario, Canada
Susy Hota
Affiliation:
Infection Prevention and Control Department, University Health Network, Toronto, Ontario, Canada Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Irene E. Armstrong
Affiliation:
Toronto Public Heath, Toronto, Ontario, Canada
Tony Mazzulli
Affiliation:
Department of Microbiology, Mount Sinai Health System and University Health Network, Toronto, Ontario, Canada
Shaindel Kestenberg
Affiliation:
Department of Health Services, University Health Network, Toronto, Ontario, Canada
Leanne K. Casaubon
Affiliation:
Department of Medicine, University of Toronto, Toronto, Ontario, Canada Division of Neurology, University Health Network, Toronto, Ontario, Canada
John Granton
Affiliation:
Department of Medicine, University of Toronto, Toronto, Ontario, Canada Department of Health Services, University Health Network, Toronto, Ontario, Canada Division of Pulmonary and Critical Care, University Health Network, Toronto, Ontario, Canada
Carly Rebelo
Affiliation:
Infection Prevention and Control Department, University Health Network, Toronto, Ontario, Canada Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada
Erika Bartels
Affiliation:
Toronto Public Heath, Toronto, Ontario, Canada
Jeff Wrana
Affiliation:
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital, Toronto, Ontario, Canada
Alon Vaisman*
Affiliation:
Infection Prevention and Control Department, University Health Network, Toronto, Ontario, Canada Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada
*
Author for correspondence: Dr Alon Vaisman, E-mail: alon.vaisman@uhn.ca

Abstract

The severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant is highly transmissible, and current vaccines may have reduced effectiveness in preventing symptomatic infection. Using epidemiological and genomic analyses, we investigated an outbreak of the variant in an acute-care setting among partially and fully vaccinated individuals. Effective outbreak control was achieved using standard measures.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

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