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Feasibility of Routinely Using Hydrogen Peroxide Vapor to Decontaminate Rooms in a Busy United States Hospital

Published online by Cambridge University Press:  02 January 2015

Jonathan A. Otter*
BIOQUELL (UK), Andover, Hampshire, United Kingdom
Matthew Puchowicz
BIOQUELL, Philadelphia, Pennsylvania
David Ryan
BIOQUELL, Philadelphia, Pennsylvania
James A. G. Salkeld
BIOQUELL, Philadelphia, Pennsylvania
Timothea A. Cooper
Hospital of Saint Raphael, New Haven, Connecticut
Nancy L. Havill
Hospital of Saint Raphael, New Haven, Connecticut
Kathy Tuozzo
Hospital of Saint Raphael, New Haven, Connecticut
John M. Boyce
Hospital of Saint Raphael, New Haven, Connecticut Yale University School of Medicine, New Haven, Connecticut
BIOQUELL (UK), 52 Royce Close, West Portway, Andover, Hampshire, SPIO 3TS, United Kingdom(


During a 22-month period at a 500-bed teaching hospital, 1,565 rooms that had housed patients infected with multidrug-resistant pathogens were decontaminated using hydrogen peroxide vapor. Hydrogen peroxide vapor decontamination required a mean time of 2 hours and 20 minutes, compared with 32 minutes for conventional cleaning. Despite the greater time required for decontamination, hydrogen peroxide vapor decontamination of selected patient rooms is feasible in a busy hospital with a mean occupancy rate of 94%.

Concise Communications
Copyright © The Society for Healthcare Epidemiology of America 2009

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