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Mutation rates at a new set of specific loci in the mouse

Published online by Cambridge University Press:  14 April 2009

Mary F. Lyon  and
T. Morris
Mary F. Lyon
Affiliation:
M.R.C. Radiobiological Research Unit, Harwell, Didcot, Berkshire, England
T. Morris
Affiliation:
M.R.C. Radiobiological Research Unit, Harwell, Didcot, Berkshire, England

Extract

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Previous measurements of specific locus mutation rates in mice had all involved the seven loci, a, b, c, d, p, s and se. An experiment was performed with the same mouse stock (C3H × 101) and the same radiation dose (600 rad) to spermatogonia as had been used previously, but employing a new group of six loci, a, bp, fz, In, pa and pe. The observed mutation rate, 5·0 × 10−8 per locus per rad, was significantly lower than that for the original seven loci, but was three to four times higher than the corresponding mutation rate in Drosophila melanogaster.

Type
Research Article
Information
Genetics Research , Volume 7 , Issue 1 , February 1966 , pp. 12 - 17
Copyright
Copyright © Cambridge University Press 1966

References

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