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Inheritance of the macrophage alloantigenic marker (Mph-1) in inbred mice

Published online by Cambridge University Press:  14 April 2009

James R. Archer
James R. Archer
Affiliation:
Searle Research Laboratories, P.O. Box 53, Lane End Road, High Wycombe, Bucks, HP12 4HL, England

Summary

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Improvements in cytotoxic technique allowed a determination to be made of the strain distribution and inheritance of Mph-1, the mouse peritoneal exudate cell alloantigen. Mph-lb, the allele in B10 lines, is inherited as a Mendelian co-dominant gene. In a 3-point backcross using the colour markers pink eye dilution (p) and chinchilla (cch) it was shown to map about 36 units from p in the order p-cch-Mph-l on chromosome 7. An alternative antigen, Mph-1.1, has been identified on strains F/St and I/StDa.

Type
Research Article
Information
Genetics Research , Volume 26 , Issue 2 , October 1975 , pp. 213 - 219
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

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