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Distribution of crossing-over in mouse chromosomes

Published online by Cambridge University Press:  14 April 2009

Mary F. Lyon
Mary F. Lyon
Affiliation:
MRC Radiobiology Unit, Harwell, Oxon, 0X11 0RD, England

Summary

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In devising maps of the positions of gene loci along chromosomes, by measurements of crossing-over, it is usual to assume that the chiasmata which give rise to the crossing-over are randomly located, unless there is evidence to the contrary. If chiasmata are in fact preferentially located at certain points or regions this not only affects mapping, but also is of interest for population genetics since it may favour the development during evolution of blocks of genes relatively undisturbed by crossing-over. Preferential localization of chiasmata is well known in a number of disparate organisms (Darlington 1965; John & Lewis, 1965), but has so far been little studied in mammals. Evidence is presented suggesting tha chiasmata are in fact non-randomly located in certain chromosomes of the mouse.

Type
Research Article
Information
Genetics Research , Volume 28 , Issue 3 , December 1976 , pp. 291 - 299
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Boer, P. de & Groen, A. (1974). Fertility and meiotic behaviour of male T70H tertiary trisomics of the mouse (Mus musculus). A case of preferential telomeric meiotic pairing in a mammal. Cytogenetics and Cell Genetics 13, 489–510.CrossRefGoogle Scholar
Collins, R. L. (1970). A new genetic locus mapped from behavioral variation in mice: audiogenic seizure prone (asp). Behavioural Genetics 1, 99–109.CrossRefGoogle ScholarPubMed
Darlington, C. D. (1965). Cytology. London: J. and A. Churchill Ltd.Google Scholar
Dunn, L. C. & Bennett, D. (1967). Sex differences in recombination of linked genes in animals. Genetical Research 9, 211–220.CrossRefGoogle ScholarPubMed
Egorov, I. K. & Blandova, Z. K. (1968). Private communication. Mouse News Letter 39, 41 & 41, 48.Google Scholar
Evans, E. P. & Phillips, R. J. S. (1975). Inversion heterozygosity and the origin of XO daughters of Bpa/ + female mice. Nature 256, 40–41.CrossRefGoogle ScholarPubMed
Green, M. C. (1975). Private communication. Mouse News Letter 53, 10.Google Scholar
Henderson, S. A. & Edwards, R. G. (1968). Chiasma frequency and maternal age in mammals. Nature 218, 22–28.CrossRefGoogle ScholarPubMed
John, B. & Lewis, K. R. (1965). The meiotic system. Protoplasmatologia 6.Google Scholar
Klein, J. (1975). Biology of the Mouse Histocompatibility-2 Complex. Berlin: Springer-Verlag.CrossRefGoogle Scholar
Klein, J. & Klein, D. (1972). Position of the translocation break T(2; 9)138Ca in linkage group IX of the mouse. Genetical Research 19, 177–179.CrossRefGoogle Scholar
Kyslikova, K. & Forejt, J. (1972). Chiasma frequency in three inbred strains of mice. Folia Biologica, Praha 18, 216–218.Google ScholarPubMed
Lyon, M. F. (1967). Private communication. Mouse News Letter, 36, 35.Google Scholar
Lyon, M. F. & Phillips, R. J. S. (1959). Crossing-over in mice heterozygous for t-alleles. Heredity 13, 23–32.CrossRefGoogle Scholar
Meredith, R. (1971). Private communication. Mouse News Letter 45, 31.Google Scholar
Miller, D. A. & Miller, O. J. (1972). Chromosome mapping in the mouse. Science 178, 949–955.CrossRefGoogle ScholarPubMed
Nesbitt, M. N. & Francke, U. (1973). A system of nomenclature for band patterns of mouse chromosomes. Chromosoma 41, 145–158.CrossRefGoogle ScholarPubMed
Phillips, R. J. S. (1968). Private communication. Mouse News Letter 39, 25.Google Scholar
Phillips, R. J. S. (1970). Private communication. Mouse News Letter 42, 27.Google Scholar
Polani, P. E. (1972). Centromere localization at meiosis and the position of chiasmata in the male and female mouse. Chromosoma 36, 343–374.CrossRefGoogle ScholarPubMed
Searle, A. G., Berry, R. J. & Beechey, C. V. (1970). Cytogenetic radiosensitivity and chiasma frequency in wild-living male mice. Mutation Research 9, 137–140.CrossRefGoogle ScholarPubMed
Stockert, E., Boyse, E. A., Sato, H. & Itakura, K. (1976). Heredity of the GIX thymocyte antigen associated with murine leukemia virus. Segregation data simulating genetic linkage (quasi-linkage). Proceedings of the National Academy of Sciences, U.S.A. 73, 2077–2081.CrossRefGoogle Scholar
Wallace, M. E. & Mallyon, S. A. (1972). Unusual recombination values and the mapping of the lethal miniature in the house mouse. Genetical Research 20, 257–262.CrossRefGoogle ScholarPubMed