Hostname: page-component-5c6d5d7d68-wtssw Total loading time: 0 Render date: 2024-08-16T01:27:28.156Z Has data issue: false hasContentIssue false

Analysis of quantitative inheritance of body size in mice IV. An Attempt to isolate polygenes*

Published online by Cambridge University Press:  14 April 2009

C. K. Chai
Affiliation:
Roscoe B. Jackson Memorial Laboratory, Bar Harbor, Maine

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The isolation of single inheritance units affecting body size in mice has been attempted. By using Large and Small mice as the parental strains, a breeding scheme has been carried out by repeated backcrossing to each strain with selection for both large and small body sizes in each backcross. The selections were started from the second backcross generations. The Small backcross was carried to the seventh generation and the Large to the fifth. Based on analysis of the means and variances for the parental strains and the backcross generations, it is tentatively concluded that a small number of, if not single, inheritance units may have been introduced from the Large to the Small mice. The ‘large’ genes appear to be dominant over the ‘small’ genes.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

Chai, C. K. (1956). Analysis of quantitative inheritance of body size in mice. I. Hybridization and maternal influence. II. Gene action and segregation. Genetics, 41, 157178.Google Scholar
Chai, C. K. (1957). Analysis of quantitative inheritance of body size in mice. III. Dominance. Genetics, 42, 602607.CrossRefGoogle ScholarPubMed
Falconer, D. S. & King, J. W. B. (1953). A study of selection limits in the mouse. J. Genet. 51, 561581.Google Scholar
MacArthur, J. W. (1944). Genetics of body size and related characters. I. Selection of small and large races of the laboratory mouse. Amer. Nat. 78, 142157.Google Scholar