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OBSTETRIC CHOLESTASIS

Published online by Cambridge University Press:  19 October 2004

ANNA P KENYON
Affiliation:
Maternal and Fetal Research Unit, St Thomas' Hospital Campus, London.
ANDREW SHENNAN
Affiliation:
Maternal and Fetal Research Unit, St Thomas' Hospital Campus, London.

Extract

Obstetric cholestasis (OC) is defined as pruritus of onset in pregnancy in association with abnormal liver function in the absence of any other identifiable liver pathology which resolves on delivery. It may be associated with adverse obstetric outcome and significant maternal morbidity. The significance of the disease has only recently been appreciated, and our understanding of its pathophysiology is in its infancy. This article will describe our current knowledge of the disease and critically review the interventions proposed to improve obstetric outcome and maternal morbidity.

Type
Research Article
Copyright
© 2004 Cambridge University Press

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OBSTETRIC CHOLESTASIS
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