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P02-393 - Genders Differences In Opiate-Dependent Patients Undergoing A Replacement Therapy Program In Spain: The Proteus Study

Published online by Cambridge University Press:  17 April 2020

C. Roncero
Affiliation:
Outpatient Drug Clinic. Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain
B. Box
Affiliation:
Medical Department, Schering-Plough Spain, Madrid, Spain
L. Miquel
Affiliation:
Outpatient Drug Clinic. Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain
G. Fuste
Affiliation:
Outpatient Drug Clinic. Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain
J. Llaudó
Affiliation:
Medical Department, Schering-Plough Spain, Madrid, Spain
N. Martínez
Affiliation:
Outpatient Drug Clinic. Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain
L. Rodríguez-Cintas
Affiliation:
Outpatient Drug Clinic. Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain
M. Casas
Affiliation:
Psychiatry Department, Hospital Universitario Vall Hebron. Universidad Autonoma Barcelona, Barcelona, Spain

Abstract

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Introduction

There are 80.000 patients undergoing replacement opiate programs in Spain, mainly methadone. Gender differences and the ratio of dual diagnosis in this population are unknown.

Objectives

To describe gender differences in the current therapeutic management of opiate-dependent patients undergoing a replacement therapy program in Spain.

Methods

624 patients from 74 centers in Spain were included between September 2008 and February 2009 in an observational, cross-sectional, multicenter study. Patients were ≥ 18 years, had a diagnosis of opiate dependence according to DSM-IV-TR criteria, were currently scheduled in a replacement therapy program in Spain and were given written informed consent.

Results

Only 16% of patients were female. Methadone average doses were significantly higher in man (57,59mg ± (SD 46,77) vs 52,81mg ± (SD 50,81) (p< 0.05)). Most women were caretaken by their partner (56.8% vs 34,2%) and man by their parents (61,6% vs 37,8) p< 0,05.Women were found to have significantly more sexual disorders than men (6% versus 2%; p=0.0316); but less delirium, dementia, amnesic and other cognitive disorders (none versus 6%; p=0.0486); schizophrenia and other psychotic disorders (3% versus 13%; p=0.0226); and adaptive disorders (2% versus 9%; 0.0427). No significant differences were found between sexes for other psychiatric comorbidities.

Conclusion

The ratio between men and women was close to 5/1, being bigger than that in the general opiate dependent Spanish population. Dual diagnosis rates vary by gender, but not in the number of diagnosis in Axis I or II. Gender differences must be considered when planning dependence services as women.

Type
Women's mental health
Copyright
Copyright © European Psychiatric Association 2010
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