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Loss of automatic processes and blunted-affect in depression: a P3 study

Published online by Cambridge University Press:  16 April 2020

A Partiot
Affiliation:
CNRS EP 53 Psychobiologie des Tempéraments à Risques
A Pierson*
Affiliation:
CNRS EP 53 Psychobiologie des Tempéraments à Risques
J Le Houezec
Affiliation:
CNRS URA 654-LENA, Psychophysiologie Cognitive, Hôpital de la Salpêtrière, Pavillon Clérambault, 75651Paris, Cedex 13, France
V Dodin
Affiliation:
CNRS URA 654-LENA, Psychophysiologie Cognitive, Hôpital de la Salpêtrière, Pavillon Clérambault, 75651Paris, Cedex 13, France
B Renault
Affiliation:
CNRS EP 53 Psychobiologie des Tempéraments à Risques
R Jouvent
Affiliation:
CNRS EP 53 Psychobiologie des Tempéraments à Risques
*
*Correspondence and reprints.
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Summary

The P3 components (P3a and P3b) of the event-related potentials have been analysed in sixteen in-patients with a major depressive episode (DSM III-R) according to their subtype - anxious-agitated and impulsive versus retarded and blunted-affect - assuming that these two opposite dimensions of the depressive mood would rely on different physiopathological mechanisms. The P3a component, which indexes automatic cognitive processes, was dramatically decreased in the retarded and blunted-affect group. This suggests that this special type of cognitive dysfunction in depression is rather related to negative symptoms than to depression itself.

Type
Original article
Copyright
Copyright © Elsevier, Paris 1993

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