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Is to Treat or Not to Treat Depressive Episode in Bipolar Disorder Type II with Trazodone?
Published online by Cambridge University Press: 15 April 2020
Abstract
Trazodone is a 5-HT(2) antagonist and 5-HT reuptake inhibitor (SARI), and an antidepressant with therapeutic effects on its target symptoms depressed mood, anxiety and insomnia [1,2]. The aim of our study is to present a possible line of treatment of a depressive episode in bipolar disorder type II with three case report.
BT is a 35-year-old Caucasian lady affected by bipolar disorder type II with a depressive episode. CA is a 40-year-old Caucasian lady affected by bipolar disorder type II with recurrent depressive episode with atypical symptoms. FR is a 38-year-old Caucasian gentleman affected by bipolar disorder type II with recurrent depressive episode. All patients are treated with trazodone immediate release subsequently increased up to 50-75 mg/day. After 6 months of treatment the patients showed a good outcome.
These case reports underscore the possibility of tailoring therapeutic strategies for the treatment of depressive episode in bipolar disorder type II. Our interest in trazodone lies in the possibility of treatment of depressive episode with the added benefit of resolution of affective symptoms, with fewer adverse effects and a well done effect in this patients. Moreover our opinions is that a therapy like trazodone with this particular profile of action, could represent a new strategy of tratment this patients. Further research is warranted to confirm the efficacy of this treatment.
- Type
- Article: 1122
- Information
- European Psychiatry , Volume 30 , Issue S1: Abstracts of the 23rd European Congress of Psychiatry , March 2015 , pp. 1
- Copyright
- Copyright © European Psychiatric Association 2015
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