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Genetics of alcohol withdrawal

Published online by Cambridge University Press:  16 April 2020

L.G. Schmidt  and
T. Sander
L.G. Schmidt
Affiliation:
Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050Berlin, Germany
T. Sander
Affiliation:
Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050Berlin, Germany
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Summary

Alcohol withdrawal is a clinically and etiologically heterogeneous syndrome caused by a complex interaction of environmental (e.g., amount of ethanol) and genetic factors. Multiple genes are considered to be involved in various components of the syndrome, each of them contributing only modestly to withdrawal vulnerability. Association studies using candidate genes of the dopamine, serotonin, gabaergic and opioidergic systems are reviewed and methodological limitations are discussed.

Keywords

alcoholismdopamineGABAgenesgeneticsopioidsserotoninwithdrawal
Type
Original Article
Information
European Psychiatry , Volume 15 , Issue 2 , March 2000 , pp. 135 - 139
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

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