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Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors

Published online by Cambridge University Press:  13 August 2021

J. García Eslava ,
A. Marzán Gutierrez ,
N. Riera Molist ,
S. Escoté Llobet  and
Q. Foguet-Boreu
J. García Eslava*
Affiliation:
Mental Health Department, Consorci Hositalari Vic, Vic, Spain
A. Marzán Gutierrez
Affiliation:
Mental Health Department, Consorci Hospitalari de Vic, Vic, Spain
N. Riera Molist
Affiliation:
Mental Health Department, Consorci Hospitalari de Vic, Vic, Spain
S. Escoté Llobet
Affiliation:
Mental Health Department, Consorci Hospitalari de Vic, Vic, Spain
Q. Foguet-Boreu
Affiliation:
Mental Health Department, Consorci Hositalari Vic, Vic, Spain
*
*Corresponding author.

Abstract

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Introduction

Schizophrenia it’s a deteriorating illness, where the cognitive impairment it’s one of the predominant components in this process. Theory of neurodevelopment, the most widely recognized, explains that cognition will depend most of it, on premorbid development. However, other factors explain this impairment, such as the cardiovascular risk factors (CVRF).

Objectives

The purpose of this study is to determine cognitive impairment and the domains affected in a sample of patients who suffered schizophrenia and almost one CVRF.

Methods

Cross-sectional study. Patients diagnosed with schizophrenia and at least one poorly controlled CVRF (diabetes, hypercholesterolemia, arterial hypertension or active smoking) were selected. Screen for Cognitive Impairment in Psychiatry (SCIP) scale was used to evaluate cognitive impairment and the domains affected.

Results

Preliminary data of twenty patients were included (60% men, mean age: 50 years). At CVRF in the sample, no diabetes was found, 75% had hypercholesterolemia, 15% arterial hypertension and 20% active smoking. SCIP scale showed deficits in word learning and delayed learning in 95% of the sample (n=19). The domain less affected was verbal fluency, affected in 55% of the sample (n=11). Additionally, moderate to severe cognitive impairment was observed in 65% of the sample (n=13).

Conclusions

More than half of the patients with schizophrenia and CVRF have a moderate to severe cognitive impairment. Intervention at CVRF could reduce the severity of cognitive impairment, improving functionality in these patients.

Keywords

schizophréniacognitive impairmentcognitive domainscardiovascular risk
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S540
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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