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Depression and quality of life in schizophrenia-spectrum

Published online by Cambridge University Press:  13 August 2021

N. Smaoui ,
S. Elleuch ,
M. Maalej Bouali ,
S. Omri ,
R. Feki ,
N. Charfi ,
L. Zouari ,
J. Ben Thabet  and
M. Maalej
N. Smaoui*
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
S. Elleuch
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
M. Maalej Bouali
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
S. Omri
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
R. Feki
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
N. Charfi
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
L. Zouari
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
J. Ben Thabet
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
M. Maalej
Affiliation:
Psychiatry C Department, Hedi chaker University hospital, sfax, Tunisia
*
*Corresponding author.

Abstract

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Introduction

The coming out of depressive disorders seems to be associated with severity of schizophrenia’s disease and with poor quality of life (QoL).

Objectives

The aim of our study was to assess the relationship between depression and QoL in patients with schizophrenia.

Methods

This is a cross-sectional and analytical study including stabilized patients with schizophrenia or schizoaffective disorder followed up in the outpatient psychiatry department at Hedi Chaker hospital university of Sfax (Tunisia), between August and October 2019. We used the Calgary Depression Scale (CDS) to evaluate depression and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q-SF) to assess QoL.

Results

We recruited 37 patients with a mean age of 49.14 years and a sex ratio of 4.66. Seventy-three (73%) of patients were followed for schizophrenia and 27% for schizoaffective disorder. They were married in 43.2% and 35.1% of patients had a regular work. According to CDS, 18.9% of patients had depression with a mean score of 2.27 (SD 2). QLESQSF mean score was 65.51. Depression was negatively correlated with Quality of Life Enjoyment and Satisfaction (r=-0.59, p<0.001). We did not find a significant difference in depression according to the socio-demographic characteristics of the respondents or the clinical features of the disease.

Conclusions

It is clear that depression in patients with schizophrenia is associated with significant functional disability. Strategies to overcome the burden of depression may instil hope for functional recovery.

Keywords

schizophréniaDepressionquality of life
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S513
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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