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Characteristics and duration of untreated illness in correlation with insight level of first time diagnosed schizophrenia patients in rural region of Latvia

Published online by Cambridge University Press:  23 March 2020

L. Berze ,
K. Pavlovs ,
K. Slikova ,
V. Bodins ,
I. Samule ,
N. Kurakina ,
I. Smonins  and
E. Rancans
L. Berze
Affiliation:
Rigas Stradins University, Department of Psychiatry and Addiction disorders, Riga, Latvia Daugavpils Psychoneurological Hospital, Department of acute psychosis, Daugavpils, Latvia
K. Pavlovs
Affiliation:
Riga Stradins University, Department of Psychiatry and Addiction disorders, Riga, Latvia
K. Slikova
Affiliation:
Riga Stradins University, Department of Psychiatry and Addiction disorders, Riga, Latvia
V. Bodins
Affiliation:
Daugavpils Psychoneurological Hospital, Department of acute psychosis, Daugavpils, Latvia
I. Samule
Affiliation:
Daugavpils Psychoneurological Hospital, Department of acute psychosis, Daugavpils, Latvia
N. Kurakina
Affiliation:
Daugavpils Psychoneurological Hospital, Department of first time psychosis, Daugavpils, Latvia
I. Smonins
Affiliation:
Daugavpils Psychoneurological Hospital, Department of differential diagnosis in psychiatry, Daugavpils, Latvia
E. Rancans
Affiliation:
Riga Stradins University, Department of Psychiatry and Addiction disorders, Riga, Latvia

Abstract

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Introduction

Improved insight level among schizophrenia patients is predictive for better illness prognosis.

Objective

Explore factors connected to insight.

Aim

Evaluate the insight level and clinical characteristics of first time hospitalized schizophrenia spectrum patients.

Methods

All consecutive first time hospitalized schizophrenia spectrum patients in a psychiatric hospital from 01.01.2016–26.09.2016. Patients were interviewed upon hospitalization and at the discharge with Scale for the assessment of positive symptoms (SAPS) and negative symptoms (SANS), Schedule of assessment of insight-extended (SAI-E), The Calgary depression scale for schizophrenia (C-sch), sociodemographic and clinical data were collected. All participants signed written informed consent and the study was approved by the Riga Stradins University Ethics committee.

Results

From 45 first episode patients, 38 met the inclusion criteria. Mean age was 37.66 years (SD: 11.48 years), the average duration of untreated illness (DUI) was 40.5 months (SD: 57.35 months). Psychopathologic symptoms and insight levels evaluated in scores in the 1st and 2nd interviews were as follows: SAPS 69.11 (SD: 20.78) and 33.61 (SD: 18.04), SANS 63.21 (SD: 25.30) and 40.95 (SD: 24.47), SAI-E 15.50 and 27.24 (SD: 13.24), P < 0.001, C-sch 8.50 (SD: 5.31) and 4.27 (SD: 2.86), P < 0.05. There was no statistically significant correlation between DUI and insight level. A higher level of insight at hospitalization correlated with higher levels of depression: r = 0.569, P < 0.001.

Conclusions

We noticed a tendency that lower insight levels might correlate with longer periods of untreated illness. We found that higher insight levels correlated with higher symptoms of depression.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster Viewing: Schizophrenia and other psychotic disorders
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. s804
Copyright
Copyright © European Psychiatric Association 2017
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