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1085 – Haematological And Biochemichal Changes In Depressed Patients

Published online by Cambridge University Press:  15 April 2020

M.N. Papaliaga ,
V.G. Saleptsis ,
N.A. Tsougenis ,
A.D. Giannoukas  and
O.D. Mouzas
M.N. Papaliaga
Affiliation:
Psychiatry, University Hospital of Larissa, Larissa, Greece
V.G. Saleptsis
Affiliation:
Vascular Surgery, University Hospital of Larissa, Larissa, Greece
N.A. Tsougenis
Affiliation:
Psychiatry, University Hospital of Larissa, Larissa, Greece
A.D. Giannoukas
Affiliation:
Vascular Surgery, University Hospital of Larissa, Larissa, Greece
O.D. Mouzas
Affiliation:
Psychiatry, University Hospital of Larissa, Larissa, Greece

Abstract

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Introduction

Several studies so far have addressed the issue of haematological and biochemical changes in depressed patients, but the results have been contradictory.

Method

Twenty four depressed patients (7 male/17 female, age:42.72±12.22) and 30 control subjects (6 male/24 female, age:43.60±10.25) were studied. Beck Depression Inventory (BDI) was used to assess their emotional state and haematological, biochemical tests were conducted. Because of the small sample sizes, statistical significance was examined using non-parametric Mann-Whitney test.

Results

As expected, patients had higher BDI total score than controls (mean±SD: 22.0±17.21 vs. 8.77±6.79, mean rank: 25.32 vs. 15.15) and higher values in most (13/21) BDI statements. Patients also had higher Hct (mean rank: 33.90 vs. 22.38), Hgb (mean rank: 33.52 vs. 22.68), urea (mean rank: 32.19 vs. 23.75), cholesterol (mean rank: 32.04 vs. 23.87) levels than controls, but lower serum glucose levels (mean rank: 21.69 vs. 32.15).

Conclusion

Although higher serum lipid levels have previously been connected with depression, to our knowledge, no such association has so far been established for higher serum urea, lower serum glucose levels, or higher Hct and Hgb.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E483
Copyright
Copyright © European Psychiatric Association 2013
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