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Variation in Susceptibility of Guinea-pigs to Diphtheria Toxin

Published online by Cambridge University Press:  15 May 2009

H. J. Sudmersen  and
A. T. Glenny
H. J. Sudmersen
Affiliation:
(From the Wellcome Physiological Research Laboratories, Brockwell Hall, Herne Hill, London, S.E.)
A. T. Glenny
Affiliation:
(From the Wellcome Physiological Research Laboratories, Brockwell Hall, Herne Hill, London, S.E.)
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1. A larger dose of toxin is necessary to kill a guinea-pig of the same weight in summer than in winter.

2. The rate of growth of guinea-pigs is more rapid in the summer months.

3. The weights of guinea-pigs are least affected by lethal doses in summer.

4. For guinea-pigs of the same weight the fatal dose increases with the age.

Type
Research Article
Information
Journal of Hygiene , Volume 9 , Issue 4 , December 1909 , pp. 399 - 408
Copyright
Copyright © Cambridge University Press 1909