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Vaccination against rubella of susceptible schoolgirls in Reading

Published online by Cambridge University Press:  15 May 2009

D. F. Rowlands
Affiliation:
Department of Health Services, County Borough of Reading
D. S. Freestone
Affiliation:
Department of Clinical Immunology, The Wellcome Research Laboratories, Beckenham, Kent
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Summary

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This study of 724 13-year-old schoolgirls in the County Borough of Reading showed that approximately 25% were susceptible to rubella. 96·1% of the 129 seronegative girls and significant numbers of girls with low rubella HAI antibody titres responded to subcutaneous vaccination with Wistar RA. 27/3 rubella vaccine. The incidence of most reactions after vaccination was similar in those who responded to vaccine and those who were initially immune but did not develop rising antibody titres, but rash, lymphadenopathy and headache occurred significantly more frequently in the susceptible group.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1971

References

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