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Studies on the agent of canine virus hepatitis (Rubarth's disease) I. Complement-fixation and precipitin tests

Published online by Cambridge University Press:  19 October 2009

N. M. Larin
N. M. Larin
Affiliation:
From the Canine Research Station of the Animal Health Trust, Kennett, Newmarket
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The preparation of purified antigen from canine hepatitis virus sources is described. This includes the manufacture of crude antigenie suspensions and their subsequent treatment to remove non-specific interfering substances.

The solubility of the antigenie substance in various solvents has been studied and its stability is briefly discussed.

The complement-fixation and precipitin tests are described in detail as they have been used for the virus studies.

Various virus-rich body tissues and fluids have been serologically tested, and the identity of antigens prepared from them as well as the antigenie similarity of the various strains of canine hepatitis virus have been established.

Type
Research Article
Information
Journal of Hygiene , Volume 49 , Issue 4 , December 1951 , pp. 410 - 426
Copyright
Copyright © Cambridge University Press 1951

References

Cox, H. R., Van Der Scheer, J., Aiston, S. & Bohnel, E. (1947). Tho purification and concentration of influenza virus by moans of alcohol preeipitation. J. Immunol. 56, 149.CrossRefGoogle Scholar
Eaton, M. D., Murphy, W. D. & Hanford, V. L. (1944). Hotorogonotic antibodies in acuto liopatitis. J. exp. Mcd. 79, 539.CrossRefGoogle Scholar
Miles, J. A. R. (1940). A sorological investigation in liopatitis using tho complomont-fixation reaction. Brit. J. exp. Path. 27, 25.Google Scholar
Olitzki, L. & Bernkopf, H. (1945). A preeipitation test in infectivo hopatitis. J. infect. Dis. 77, 60.CrossRefGoogle Scholar
Parry, H. B. (1950). Viral hepatitis of dogs (Rubarth's disease). I; Clinical and pathological observations on a spontaneous opidomic. Vet. Bee. 62, 559.Google Scholar
Parry, H. B., Larin, N. M. & Platt, H. (1951). Studies on tho agent of canine hepatitis (Rubarth's disease). II. The pathology and pathogenosis of tho experimental diseaso produced by four strains of virus. J. Hyg. Camb. 49, 482.Google Scholar
Rivers, T. M. (1948). Viral and Rickettsial Infections of Man. London: J. B. Lippincott Co.Google Scholar
Rubarth, S. (1947). An acuto virus diseaso with liver lesion in dogs. (Hepatitis contagiosa cam's). Ada path microbiol. Scand., Suppl., 69.Google Scholar
Sabin, A. B. & Buescher, E. L. (1950). Unique physico-chemical properties of Japanese Bencophalitis virus haomagglutinin. Proc. Soc. exp. Biol. N.Y., 74, 222.CrossRefGoogle Scholar