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Respiratory disease in a colony of rats: I. The natural disease

Published online by Cambridge University Press:  15 May 2009

W. Lane-Petter
Affiliation:
Houghton, Huntingdon
R. J. Olds
Affiliation:
Department of Pathology, University of Cambridge
M. R. Hacking
Affiliation:
Carworth Europe, Alconbury, Huntingdon
M. E. Lane-Petter
Affiliation:
Carworth Europe, Alconbury, Huntingdon
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Summary

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An epidemic of acute respiratory disease in a colony of CFE rats is described, the main laboratory findings are recorded and its aetiology discussed.

The epidemic showed that severe respiratory disease varying from peracute to chronic was associated with infection of the lungs with a mycoplasma but that mycoplasmas could be present in rats, even in the lungs, without signs of disease, thus suggesting that one or more other factors were involved. It is also evident that there are strain differences in the susceptibility of rats to this disease.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1970

References

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