Hostname: page-component-8448b6f56d-qsmjn Total loading time: 0 Render date: 2024-04-24T02:36:12.979Z Has data issue: false hasContentIssue false
  • English
  • Français

Reservoir animals for nephropathia epidemica in Norway: indications of a major role for the bank vole (C. glareolus) in comparison with the woodmouse (A. sylvaticus)

Published online by Cambridge University Press:  19 October 2009

Ann-Inger Sommer ,
T. Traavik ,
R. Mehl ,
B. P. Berdal  and
J. M. Dalrymple
Ann-Inger Sommer
Affiliation:
Institute of Medical Biology, University of Tromso, and the Virological Laboratory, Regional Hospital of Tromso, Norway
T. Traavik
Affiliation:
Institute of Medical Biology, University of Tromso, and the Virological Laboratory, Regional Hospital of Tromso, Norway
R. Mehl
Affiliation:
Laboratory for Medical Entomology, National Institute of Public Health, Oslo, Norway
B. P. Berdal
Affiliation:
Norwegian Defence Microbiological Laboratory, Oslo, Norway
J. M. Dalrymple
Affiliation:
U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland, U.S.A.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Small rodents were collected live in two different locations within a nephropathia epidemica (NE) endemic area, and tested for both antiviral serum antibodies and viral antigens in lung sections. In one location, only Apodemus sylvaticus (woodmice) were found in the traps, in the other, both A. sylvaticus and Clethrionomys glareolus (bank voles) were collected.

Among the woodmice from the former location the prevalence of NE virus markers was significantly lower than for either woodmice or bank voles from the other location, and no NE antigen-positive animals was found. The woodmice co-existing with bank voles had a lower prevalence of NE antigen and antibodies than the bank voles, and fewer woodmice had both antibodies and antigen. The results emphasize the important role of bank voles as a major NE virus reservoir and probable source of human infections.

Type
Research Article
Information
Journal of Hygiene , Volume 94 , Issue 1 , February 1985 , pp. 123 - 127
Copyright
Copyright © Cambridge University Press 1985

References

REFERENCES

Brummer-Korvenkontio, M., Vaheri, A., Hovi, T., Von Bonsdorff, C. H., Vuorimies, J., Manni, T., Penttinen, K., Oker-Blom, N. & Lahtevirta, J. (1980). Nephropathia epidemica: detection of antigen in bank voles and serologic diagnosis of human infection. Journal of Infectious Diseases 141, 131–137.CrossRefGoogle ScholarPubMed
Friman, G., French, G. R., Hambraeus, L. & Beisel, W. R. (1980). Scandinavian epidemic nephropathy and Korean hemorrhagic fever. Lancet ii, 100.CrossRefGoogle Scholar
Friman, G., French, G. R., Hambraeus, L., Beisel, W. R. & Ibbade, N. G. (1981). Serum antibodies reactant with Korean hemorrhagic fever agent in Scandinavian Epidemic (endemic) nephropathy (nephropathia epidemica), demonstrated by immunofluorescence utilizing an in vitro antigen source. Scandinavian Journal of Infectious Diseases 13, 89–93.CrossRefGoogle ScholarPubMed
Gavrilovskaya, I. N., Apekina, N. S., Myasnikov, Yu. A., Bernshtein, A. D., Ryltseva, E. V., Gorbachkova, E. A. & Chumakov, M. P. (1983). Features of circulation of Haemorrhagic fever with renal syndrome (HFRS) virus among small mammals in the European U.S.S.R. (brief report). Archives of Virology 75, 313–316.CrossRefGoogle Scholar
Lähtevirta, J. (1971). Nephropathia epidemica in Finland. A clinical, histological and epidemiological study. Annals of Clinical Research 3, supplement 8.Google Scholar
LeDuc, J. W., Smith, G. A., Bagley, L. R., Hasty, S. E. & Johnson, K. M. (1982). Preliminary evidence that Hantaan or a closely related virus is enzootic in domestic rodents (letter). New England Journal of Medicine 307, 624.Google Scholar
Lee, H. W., French, G. R., Lee, P. W., Baek, L. J., Tsuchiya, K. & Foulke, R. S. (1981). Observations on natural and laboratory infection of rodents with the etiologic agent of Korean hemorrhagic fever. American Journal of Tropical Medicine and Hygiene 30. 477–482.CrossRefGoogle ScholarPubMed
Lee, H. W., Lee, P. W., Lahtevirta, J. & Brummer-Korvenkontio, M. (1979). Aetiological relationship between Korean hemorrhagic fever and Nephropathia epidemica. Lancet i, 186–187.Google Scholar
Svedmyr, A., Lee, H. W., Berglund, A., Hoorn, B., Nystrom, K. & Gajdusek, D. C. (1979). Epidemic nephropathy in Scandinavia is related to Korean haemorrhagic fever. Lancet i, 100.CrossRefGoogle Scholar
Traavik, T. (1979). Tick- and mosquito-associated viruses in Norway. Thesis, University of Tromso, Norway.Google Scholar
Traavik, T., Mehl, R., Berdal, B. P., Lund, S. & Dalrymple, J. M. (1983). Nephropathia epidemica in Norway: description of serological response in human disease and implication of rodent reservoirs. Scandinavian Journal of Infectious Diseases 15, 11–16.CrossRefGoogle ScholarPubMed
Traavik, T., Sommer, A-I., Mehl, R., Berdal, B. P., Stavem, K., Hunderi, O. & Dalrymple, J. M. (1984). Nephropathia epidemica in Norway: antigen and antibodies in rodent reservoirs and antibodies in selected human populations. Journal of Hygiene 93, 139–146.CrossRefGoogle ScholarPubMed
Tsai, T. F., Dauer, S. P., Sasso, D. R., McCormick, J. B., Bradford, H., Caraway, C. T., McFarland, L. M., Medrano, O. & Saulie, G. (1982). Preliminary evidence that Hantaan or a closely related virus is enzootic in domestic rodents (letter). New England Journal of Medicine 307, 623.Google Scholar