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Old and new techniques together resolve a problem of infection by Salmonella typhimurium

Published online by Cambridge University Press:  19 October 2009

D. J. Platt
Affiliation:
University Department of Bacteriology, Royal Infirmary, Castle Street, Glasgow
D. J. Brown
Affiliation:
University Department of Bacteriology, Royal Infirmary, Castle Street, Glasgow
D. C. Old
Affiliation:
Department of Medical Microbiology, University of Dundee Medical School, Ninewells Hospital, Dundee
R. M. Barker
Affiliation:
Department of Medical Microbiology, University of Dundee Medical School, Ninewells Hospital, Dundee
D. S. Munro
Affiliation:
Scottish Salmonella Reference Laboratory, Stobhill General Hospital, Glasgow
J. Taylor
Affiliation:
Scottish Salmonella Reference Laboratory, Stobhill General Hospital, Glasgow
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Summary

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Isolates of Salmonella typhimurium, recovered over a 9-month period from a child with gastroenteritis, were characterized by biotyping, phage-typing and plasmid-profile analysis. Because the data from the different methods were discrepant, it was difficult to establish whether her infection was due to a single strain that had changed character in vivo or was due to recurrent infections with different, unrelated strains. Restriction-enzyme fingerprinting of the plasmids from the different isolates provided an explanation for the initial discrepancy and highlighted a source of potential confusion in epidemiological studies.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1987

References

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