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Meningococcal infections in Scotland 1972–82

Published online by Cambridge University Press:  19 October 2009

R. J. Fallon ,
W. M. Brown  and
W. Lore
R. J. Fallon
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
W. M. Brown
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
W. Lore
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
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Strains of Neisseria meningitidis isolated from patients with meningitis or septicaemia without meningitis in Scotland during the years 1972–82 have been reviewed together with details of the age, sex, disease and outcome of the patients from whom they were isolated. A total of 1185 strains were isolated, of which 927 were examined at the Meningococcal Reference Laboratory (Scotland): 19·3% were of serogroup A, 63% of group B, 9·6% of group C, 6% of W135 and 1·6% of other groups. Non-groupable strains were rare. Disease was most common in the first years of life but there was a difference in the age distribution of disease due to the different serogroups, the proportion of disease due to group B being smaller in adults than that due to other serogroups. The overall mortality in meningitis was 7·5% and in septicaemia was 20·6%, although there were differences between the rates for the various serogroups. The serogroup distribution differed in disease as opposed to meningococci isolated from carriers although group B strains were predominant in both series. Overall, approximately 15% of strains were resistant to sulphadiazine, the proportion of resistant group A strains being higher than that of other serogroups.

Type
Research Article
Information
Journal of Hygiene , Volume 93 , Issue 2 , October 1984 , pp. 167 - 180
Copyright
Copyright © Cambridge University Press 1984

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