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The Mechanism of the Agglutination Reaction

Published online by Cambridge University Press:  15 May 2009

Henry Priestley
Henry Priestley
Affiliation:
(From The Australian Institute of Tropical Medicine.)
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Since Gruber and Nicolle expressed the opinion that the agglutination of bacteria by specific immune sera was due to the surfaces of the bacteria becoming viscous under the influence of the specific sera, many theories have been advanced aiming at a more complete explanation of the reaction. Bordet (1899) considered that the agglutinins by uniting with the agglutinable substances lead to changes in molecular attraction between the elements affected, either as among themselves, or between them and the surrounding fluid. He distinguished the two phases of the reaction, (1) the interaction between the agglutinin and the bacteria, and (2) the agglomeration of the bacteria.

Type
Research Article
Information
Journal of Hygiene , Volume 15 , Issue 4 , February 1917 , pp. 485 - 504
Copyright
Copyright © Cambridge University Press 1917

References

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