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Intravenous infusion bottle plugs as a source of microbial contamination

Published online by Cambridge University Press:  15 May 2009

C. J. Holmes  and
M. O. Allwood
C. J. Holmes
Affiliation:
Department of Pharmacy, The University, Manchester 13
M. O. Allwood
Affiliation:
Department of Pharmacy, The University, Manchester 13
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Summary

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A technique was described for the artificial contamination of the upper surface of intravenous infusion container plugs with viable micro-organisms. This technique was employed to assess the adequacy of decontamination of two designs of plug by the use of antiseptic swabbing. Results indicated that the MRO plug surface was more difficult to sterilize than that of the Tra venol plug. The possibility of contamination of the infusion fluid during insertion of the giving-set needle was examined. Results indicated that there was a risk of contamination through the administration-set port of the MRC plug if swabbing was inadequate.

Type
Research Article
Information
Journal of Hygiene , Volume 77 , Issue 3 , December 1976 , pp. 315 - 320
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Arnold, T. R., & Hepler, C. D. (1971). Bacterial contamination of intravenous fluids opened in unsterile air. American Journal of Hospital Pharmacy, 28, 614–19.Google ScholarPubMed
D'Arcy, P. F., & Woodside, W. (1973). Drug additives – a potential source of bacterial contamination of infusion fluids? Lancet ii, 96.CrossRefGoogle Scholar
Deeb, E. N., & Natsios, G. A. (1971). Contamination of intravenous fluids by bacteria and fungi during preparation and administration. American Journal of Hospital Pharmacy 28, 764–7.Google ScholarPubMed
Duma, R. J., Warner, J. F., & Dalton, H. P. (1971). Septicemia from intravenous infusions. New England Journal of Medicine 284, 257–60.CrossRefGoogle ScholarPubMed
Hambleton, R. (1964). The germination of spores of Bacillus megaterium in the presence of cetrimide. M.Sc. thesis, University of Manchester.Google Scholar
Letceer, K. I., Thrupp, L. D., Shapiro, D. J., & Boersma, J. E. (1972). In-use contamination of intravenous solutions in flexible plastic containers. American Journal of Hospital Pharmacy 29, 673.Google Scholar
Maki, D. G., Goldman, D. A., & Rhame, F. S. (1973). Infection control in intravenous therapy. Annals of Internal Medicine 79, 867–87.CrossRefGoogle ScholarPubMed
Michaels, L., & Ruebner, B. (1953). Growth of bacteria in intravenous infusions. Lancet i, 773.Google Scholar