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Intracellular growth of some viruses of the pox group. An electron microscopic study of infected chick chorionic cells

Published online by Cambridge University Press:  15 May 2009

T. H. Flewett
T. H. Flewett
Affiliation:
Department of Bacteriology, University of Leeds
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Sections of chorio-allantoic membranes fixed at intervals after infection with large doses of vaccinia virus showed almost homogeneous areas appearing in the cytoplasm after 4 hr.; these areas contained immature forms of virus which had a thin surface membrane and an eccentric ‘nucleoid’, and were surrounded by mitochondria. Mature forms of virus, having a larger central nucleus-like structure and a thicker cortex, were first found in areas of virus growth 10 hr. after inoculation. Similar immature and mature forms were found in cells infected with fowl-pox, myxomatosis and ectromelia viruses. It is concluded that the immature forms are of low infectivity or not infective.

Type
Research Article
Information
Journal of Hygiene , Volume 54 , Issue 3 , September 1956 , pp. 393 - 400
Copyright
Copyright © Cambridge University Press 1956

References

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