Hostname: page-component-848d4c4894-xfwgj Total loading time: 0 Render date: 2024-06-23T02:46:57.987Z Has data issue: false hasContentIssue false
  • English
  • Français

Influenza A(H1N1) viruses of the 1977/78 outbreak: isolation and haemagglutination properties

Published online by Cambridge University Press:  15 May 2009

R. Pyhälä  and
R. Visakorpi
R. Pyhälä
Affiliation:
National Influenza Centre, Central Public Health Laboratory, Helsinki, Finland
R. Visakorpi
Affiliation:
National Influenza Centre, Central Public Health Laboratory, Helsinki, Finland
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

During the H1N1 outbreak of 1977/8, the virus was isolated in embryonated eggs from 59 out of 76 patients (78%) with the serologically confirmed infection. A similar isolation frequency has been achieved during a period of six H3N2 outbreaks since 1972/3. The H1N1 strains were isolated less frequently from late specimens (collected 4–6 days from the onset of illness) and more often only in the second passage compared with the H3N2 viruses. The new H1N1 strains resembled those prevalent in the 1950s with respect to their ability to agglutinate erythrocytes of certain laboratory animals and to be eluted from these, and thus differed from the H3N2 viruses.

Type
Research Article
Information
Journal of Hygiene , Volume 82 , Issue 1 , February 1979 , pp. 81 - 88
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Casey, H. L. (1965). Standardized diagnostic complement fixation method and adaptation to micro test. II. Adaptation of LBCF method to micro technique. Public Health Monographs 74, 31–34.Google ScholarPubMed
Chu, C. M. (1948). Agglutination of red blood cells of different animal species by influenza and Newcastle disease viruses. Journal of Hygiene 46, 239–246.CrossRefGoogle ScholarPubMed
Coleman, M. T. & Dowdle, W. R. (1969). Properties of the Hong Kong influenza virus. 1. General characteristics of the Hong Kong virus. Bulletin of the World Health Organization 41, 415–418.Google Scholar
Douglas, R. G. Jr (1975). Influenza in man. In The Influenza Viruses and Influenza (ed. Kilbourne, E. D.), p. 406. New York, London: Academic Press.Google Scholar
Dowdle, W. R. & Schild, G. C. (1975). Laboratory propagation of human influenza viruses, experimental host range, and isolation from clinical material. In The Influenza Viruses and Influenza (ed. Kilbourne, E. D.), p. 263. New York, London: Academic Press.Google Scholar
Hoyle, L. (1968). The influenza viruses. In Virology Monographs, p. 201. Wien, New York: Springer-Verlag.Google Scholar
Ivanova, N. A., Taros, L. Yu, Grinbaum, E. B., Rumel, N. B., Kamforin, L. E. & Luzyanina, T. YA. (1976). Results of virological and serological studies of three influenza A Hong Kong epidemics in Leningrad. Journal of Hygiene, Epidemiology, Microbiology and Immunology 20, 186–194.Google ScholarPubMed
Nagler, F. P., Burr, M. M. & Gillen, A. L. (1951). The influenza virus epidemic in Canada during January-February 1951. Canadian Journal of Public Health 42, 367–74.Google ScholarPubMed
Nagler, F. P., van Rooyen, C. E. & Sturdy, J. H. (1949). An influenza virus epidemic at Victoria Island, N.W.T., Canada. Canadian Journal of Public Health 40, 457–65.Google ScholarPubMed
Pyhälä, R. (1978). Antibodies to influenza A viruses of the H1N1 subtype: age-dependency and effect of recent infections with H3N2 viruses. FEMS Microbiology Letters 3, 165–7.CrossRefGoogle Scholar
Pyhälä, R. & Aho, K. (1975). Serum HI antibody and protection against influenza: a follow-up survey at community level of three epidemics caused by different H3N2-variants. International Journal of Epidemiology 4, 127–9.CrossRefGoogle ScholarPubMed
Pyhälä, R, Aho, K., Kantanen, M.-L. & Koistinen, J. (1976). Virus antibody levels and IgA deficiency. Scandinavian Journal of Immunology 5, 1093–6.CrossRefGoogle ScholarPubMed
Pyhälä, R & Kleemola, M. (1976). The value of complement fixation and haemagglutination inhibition tests in the diagnosis of influenza A. Acta virologica 20, 66–9.Google ScholarPubMed
Robinson, R. Q. & Dowdle, W. R. (1969). Influenza viruses. In Diagnostic Procedures for Viral and Rickettsial Infections (ed. Lennette, E. H. and Schmidt, N. J.), pp. 426–7. New York: American Public Health Association.Google Scholar
Irene, Schulze T. (1975). The biologically active proteins of influenza viruses: the haemagglutinin. In The Influenza Viruses and Influenza (ed. Kilbourue, E. D.), p. 78. New York, London: Academic Press.Google Scholar
Wassilewa, L. (1977). Cell receptors for paramyxoviruses. Archives of Virology 54, 299–305.CrossRefGoogle ScholarPubMed
Zalan, E., Pukitis, D., Rhodes, A. J. & Labzoffsky, N. A. (1973). Interference of influenza-specific IgA antibodies present in throat washings with isolation of the virus. Archiv für die gesamte Virusforschung 42, 307–10.CrossRefGoogle ScholarPubMed