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The importance of agglutinin production in mice in the determination of the definitive serotype of Bordetella pertussis

Published online by Cambridge University Press:  15 May 2009

Caroline J. Bronne–Shanbury
Caroline J. Bronne–Shanbury
Affiliation:
The Lister Institute of Preventive Medicine, Elstree, Hertfordshire WD6 3AX
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Summary

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A schedule for the routine serotyping of strains of Bordetella pertussis based on agglutinin production in mice to the K-antigens has been worked out. Mice have been found as satisfactory as rabbits but far more economical for the production of the very small volumes of serum which are required. Agglutinin production, used in conjunction with direct agglutination, provides definitive information about serotype.

Type
Research Article
Information
Journal of Hygiene , Volume 76 , Issue 2 , April 1976 , pp. 257 - 264
Copyright
Copyright © Cambridge University Press 1976

References

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