Hostname: page-component-848d4c4894-wg55d Total loading time: 0 Render date: 2024-06-03T10:00:42.141Z Has data issue: false hasContentIssue false

Hepatitis B serology in Greek prostitutes: significance of the different serum markers

Published online by Cambridge University Press:  15 May 2009

Evangelia Kaklamani
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
Athena Kyriakidou
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
Dimitri Trichopoulos
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
George Papoutsakis
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
Ivoni Koumandaki
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
Dimitri Karalis
Affiliation:
The Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Goudi, Athens 609, Greece
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

One hundred and ninety-eight prostitutes (mean age 41·8 years) and 117 control women of low socio-economic class (mean age 43·8 years) were tested by solid-phase radioimmunoassay for hepatitis B surface antigen (HBsAg), its antibody (anti-HBs) and antibody to hepatitis B core antigen (anti-HBc). The prevalence of HBsAg was higher among prostitutes (11% v. 4%, P ∼ 0·06). This difference was accounted for by the higher infection rate of prostitutes to hepatitis B virus (HBV) (97% v. 45%, P < 10−6), since the proportion of HBsAg carriers among those infected was practically the same between the two groups (11% v 9%). Among the previously infected prostitutes who did not become carriers the majority (75%) were positive for both anti-HBc and anti-HBs, whereas among control women about half (52%) were positive only for anti-HBc.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1980

References

REFERENCES

Ellis, W. R., Coleman, J. C., Fluker, J. L., Keeling, P. W. N., Banatvala, J. E., Murray-Lyon, M. I., Evans, B. A., Bull, J., Simmons, P. D., Willcox, J. R. & Thompson, R. P. H. (1979). Liver disease among homosexual males. Lancet i, 903–5.CrossRefGoogle Scholar
Hersh, T., Melnick, J., Goyal, R. K. & Hollinger, F. B. (1971). Nonparenteral transmission of viral hepatitis type B (Australia antigen-associated serum hepatitis). New England Journal of Medicine 285, 1363–6.CrossRefGoogle ScholarPubMed
Hoofnagle, J. H., Seeff, L. B., Bales, Z. B., Zimmerman, H. J. & The Veterans Administration Hepatitis Cooperative Study Group (1978 a). Type B hepatitis after transfusion with blood containing antibody to hepatitis B core antigen. New England Journal of Medicine 298, 1379–83.CrossRefGoogle ScholarPubMed
Hoofnagle, J. H., Seeff, L. B., Bales, Z. B., Gerety, R. J. & Tabor, E. (1978 b). Serologic responses in HB. In Viral Hepatitis (ed. Vyas, G. N., Cohen, S. N. and Schmid, R.), chapter 22, PP. 219–42. Philadelphia: Franklin Institute Press.Google Scholar
Howard, C. R. & Burrell, C. J. (1976). Structure and nature of Hepatitis B antigen. Progress in Medical Virology 22, 36103.Google ScholarPubMed
Jeffries, D. J., James, W. H., Jefferiss, F. J. G., MacLeod, K. G. & Willcox, R. R. (1973). Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic. British Medical Journal ii, 455–56.CrossRefGoogle Scholar
Kaklamani, E., Trichopoulos, D., Papaevangelou, G., Drouga, M., Karalis, D. & Papoutsakis, G. (1978). T-lymphocytes and hepatitis B serology. Infection 6, 290–3.CrossRefGoogle ScholarPubMed
Krugman, S., Overby, L. R., Mushahwar, I. K., Ling, C. M., Frösner, G. G. & Deinhardt F. (1979). Viral hepatitis, type B. New England Journal of Medicine 300, 101–6.CrossRefGoogle ScholarPubMed
Mantel, N. (1963). Chi-square tests with one degree of freedom; extensions of the Mantel—Haenszel procedure. Journal of the American Statistical Association 58, 690.Google Scholar
Omata, M., Afroudakis, A., Liew, C. T., Ashcavai, M. & Peters, R. L. (1978). Comparison of serum hepatitis B surface antigen (HBsAg) and serum anticore with tissue HBsAg and hepatitis B core antigen (HBcAg). Gastroenterology 75, 1003–9.CrossRefGoogle ScholarPubMed
Papaevangelou, G., Trichopulos, D., Kremastinou, T. & Papoutsakis, G. (1974). Prevalence of hepatitis B antigen and antibody in prostitutes. British Medical Journal, ii, 256–8.CrossRefGoogle Scholar
Papaevangelou, G., Kyriakidou, A., Vissoulis, C. & Trichopoulos, D. (1976). Seroepidemiological study of HBV infections in Athens, Greece. Journal of Hygiene 76, 229–34.CrossRefGoogle ScholarPubMed
Szmuness, W., Hoofnagle, J. H., Stevens, C. E. & Prince, A. M. (1976). Antibody against the hepatitis type B core antigen. American Journal of Epidemiology 104, 256–62.CrossRefGoogle ScholarPubMed
Trichopoulos, D., Papaevangelou, G., Violaki, M., Vissoulis, Ch., Sparros, L. & Manousos, O. N. (1976). Geographic correlation between mortality from primary hepatic carcinoma and prevalence of hepatitis B surface antigen in Greece. British Journal of Cancer 34, 83–7.CrossRefGoogle ScholarPubMed
Zuckerman, J. A. (1978). Developments in viral hepatitis. Journal of Medical Virology 3, 18.CrossRefGoogle ScholarPubMed