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Growth agglutination and growth inhibition tests in the diagnosis of brucellosis

Published online by Cambridge University Press:  15 May 2009

K. R. Mittal  and
I. R. Tizard
K. R. Mittal
Affiliation:
Department of Veterinary Microbiology and Immunology Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
I. R. Tizard
Affiliation:
Department of Veterinary Microbiology and Immunology Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
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Summary

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Growth agglutination and growth inhibition tests were established for the diagnosis of Brucella abortus infection. The former involves the agglutination of living organisms while the latter is a bactericidal test. Using mouse, guinea-pig, rabbit and bovine serum it was shown that the growth agglutination test is approximately ten times, and the growth inhibition test one hundred times, more sensitive than the conventional tube agglutination test. It is suggested that these techniques may be of assistance in diagnosing bovine brucellosis in situations in which the tube agglutination test results are suspected of being falsely negative.

Type
Research Article
Information
Journal of Hygiene , Volume 83 , Issue 2 , October 1979 , pp. 295 - 304
Copyright
Copyright © Cambridge University Press 1979

References

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