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Contaminant viruses in two live virus vaccines produced in chick cells

Published online by Cambridge University Press:  15 May 2009

R. J. C. Harris ,
R. M. Dougherty ,
P. M. Biggs ,
L. N. Payne ,
A. P. Goffe ,
A. E. Churchill  and
R. Mortimer
R. J. C. Harris
Affiliation:
Division of Experimental Biology and Virology Imperial Cancer Research Fund, London, N. W. 7
R. M. Dougherty
Affiliation:
Division of Experimental Biology and Virology Imperial Cancer Research Fund, London, N. W. 7
P. M. Biggs
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon
L. N. Payne
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon
A. P. Goffe
Affiliation:
Department of Virology, Wellcome Research Laboratories, Beckenham, Kent
A. E. Churchill
Affiliation:
Department of Virology, Wellcome Research Laboratories, Beckenham, Kent
R. Mortimer
Affiliation:
R.A.F. Institute of Pathology and Tropical Medicine, Halton, Bucks
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Samples of yellow-fever vaccine prepared from homogenized chick embryos, and of an experimental measles vaccine prepared from chick embryo cells, have each been shown to contain a contaminant virus similar in properties to an avian leukosis virus. Young adult males injected with the yellow-fever vaccine did not develop neutralizing antibodies for Rous sarcoma virus.

Type
Research Article
Information
Journal of Hygiene , Volume 64 , Issue 1 , March 1966 , pp. 1 - 7
Copyright
Copyright © Cambridge University Press 1966

References

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