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Acquisition of a drug resistance plasmid converts Salmonella enteritidis phage type 4 to phage type 24

Published online by Cambridge University Press:  15 May 2009

J. A. Frost ,
L. R. Ward  and
B. Rowe
J. A. Frost
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
L. R. Ward
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
B. Rowe
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
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Summary

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Salmonella enteritidis accounted for 55% of the 27478 salmonellae isolated from humans in England and Wales during 1988. Within this serotype phage type 24 has increased from 24 isolations in 1987 to 201 in 1988. The high frequency of drug resistance in this phage type has been shown to be due to the presence of plasmids belonging to Inc N and coding for resistance to a range of antimicrobial drugs among which resistance to ampicillin, streptomycin, tetracycline (AST) and T predominate. These plasmids are phage-type determining and convert strains of phage type 4 to phage type 24.

Type
Research Article
Information
Epidemiology & Infection , Volume 103 , Issue 2 , October 1989 , pp. 243 - 248
Copyright
Copyright © Cambridge University Press 1989

References

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