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Fitness and beyond: Preparing for the arrival of GM crops with ecologically important novel characters

Published online by Cambridge University Press:  07 May 2009

Mike Wilkinson
Affiliation:
Institute of Biological Environmental and Rural Sciences, Edward Llwyd Building, Wales University, Aberystwyth, Ceredigion SY23 3DA, UK
Mark Tepfer
Affiliation:
Plant Virology Group, ICGEB Biosafety Outstation, Via Piovega 23, 31056 Ca' Tron di Roncade, Italy

Abstract

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The seemingly inexorable expansion of global human population size, significant increases in the use of biofuel crops and the growing pressures of multifunctional land-use have intensified the need to improve crop productivity. The widespread cultivation of high-yielding genetically modified (GM) crops could help to address these problems, although in doing so, steps must also be taken to ensure that any gene flow from these crops to wild or weedy recipients does not cause significant ecological harm. It is partly for this reason that new GM cultivars are invariably subjected to strict regulatory evaluation in order to assess the risks that each may pose to the environment. Regulatory bodies vary in their approach to decision-making, although all require access to large quantities of detailed information. Such an exhaustive case-by-case approach has been made tractable by the comparative simplicity of the portfolio of GM crops currently on the market, with four crops and two classes of traits accounting for almost all of the area under cultivation of GM crops. This simplified situation will change shortly, and will seriously complicate and potentially slow the evaluation process. Nowhere will the increased diversity of GM crops cause more difficulty to regulators than in those cases where there is a need to assess whether the transgene(s) will enhance fitness in a non-transgenic relative and thereafter cause ecological harm. Current practice to test this risk hypothesis focuses on attempting to detect increased fitness in the recipient. In this paper we explore the merits and shortcomings of this strategy, and investigate the scope for developing new approaches to streamline decision-making processes for transgenes that could cause unwanted ecological change.

Type
Research Article
Copyright
© ISBR, EDP Sciences, 2009

References

Aaziz, R, Tepfer, M (1999) Recombination in RNA viruses and virus-resistant transgenic plants. J. Gen. Virol. 80: 13391346 CrossRef
Angevin, F, Klein, EK, Choimet, C, Gauffreteau, A, Lavigne, C, Messean, A, Meynard, JM (2008) Modelling impacts of cropping systems and climate on maize cross-pollination in agricultural landscapes: The MAPOD model. Eur. J. Agron. 28: 471484 CrossRef
Aono, M, Wakiyama, S, Nagatsu, M, Nakajima, N, Tamaoki, M, Kubo, A, Saji, H (2006) Detection of feral transgenic oilseed rape with multiple-herbicide resistance in Japan. Environ. Biosafety Res. 5: 7787 CrossRef
Bailey JP, Wisskirchen R (2006) The distribution and origins of Fallopia × bohemica (Polygonaceae) in Europe. Nordic J. Bot. 24 173–199
Bailey, JP, Bimova, K, Mandak, B (2007) The potential role of polyploidy and hybridisation in the further evolution of the highly invasive Fallopia taxa in Europe. Ecol. Res. 22: 920928 CrossRef
Beaumont, MA, Zhang, WY, Balding, DJ (2002) Approximate Bayesian computation in population genetics. Genetics 162: 20252035 PubMed
Bratteler, M, Baltisberger, M, Widmer, A (2006) QTL analysis of intraspecific differences between two Silene vulgaris ecotypes. Ann. Bot.-London 98: 411419 CrossRef
Brummell, DA, Howie, WJ, Ma, C, Dunsmuir, P (2002) Postharvest fruit quality of transgenic tomatoes suppressed in expression of a ripening-related expansin. Postharvest Biol. Tec. 25: 209220 CrossRef
Bullock, JM, Pywell, RF, Coulson-Phillips, SJ (2008) Managing plant population spread: Prediction and analysis using a simple model. Ecol. Appl. 18: 945953 CrossRef
Cai, L, Zhou, BW, Guo, XL, Dong, CH, Hu, XJ, Hou, MS, Liu, SY (2008) Pollen-mediated gene flow in Chinese commercial fields of glufosinate-resistant canola (Brassica napus). Chinese Sci. Bull. 53: 23332341
Capalbo, DMF, Hilbeck, A, Andow, D, Snow, A, Bong, BB, Wan, FH, Fontes, EMG, Osir, EO, Fitt, GP, Johnston, J, Songa, J, Heong, KL, Birch, ANE (2003) Brazil and the development of international scientific biosafety testing guidelines for transgenic crops. 8th International Colloquium on Invertebrate Pathology and Microbial Control/35th Annual Meeting of the SIP/6th International Conference on Bacillus thuringiensis, August, 2002, Iguassu Falls, Brazil. J. Invertebr. Pathol. 83: 104106 CrossRef
Cardwell, R, Kerr, WA (2008) Protecting biotechnology IPRs in developing countries: Simple analytics of a levy solution. J. Agr. Econ. 59: 217236 CrossRef
Cheffings C, Farrell L (2005) The Vascular Plant Red Data List for Great Britain. Peterborough: Joint Nature Conservation Committee
Crawley, MJ, Brown, SL (1995) Seed limitation and the dynamics of feral oilseed rape on the M25 Motorway. P. Roy. Soc. B-Biol. Sci. 259: 4954 CrossRef
Crawley, MJ, Hails, RS, Rees, M, Kohn, D, Buxton, J (1993) Ecology of transgenic oilseed rape in natural habitats. Nature 363: 620623 CrossRef
de Torres-Zabala, M, Truman, W, Bennett, MH, Lafforgue, G, Mansfield, JW, Egea, PR, Bogre, L, Grant, M (2007) Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease. EMBO J. 26: 14341443 CrossRef
de Wispelaere, M, Gaubert, S, Trouilloud, S, Belin, C, Tepfer, M (2005) A map of the diversity of RNA3 recombinants appearing in plants infected with Cucumber mosaic virus and Tomato aspermy virus. Virology 331: 117127 CrossRef
Devaux, C, Lavigne, C, Falentin-Guyomarc'h, H, Vautrin, S, Lecomte, J, Klein, EK (2005) High diversity of oilseed rape pollen clouds over an agro-ecosystem indicates long-distance dispersal. Mol. Ecol. 14: 22692280 CrossRef
Eveno, E, Collada, C, Guevara, MA (2008) Contrasting patterns of selection at Pinus pinaster Ait. drought stress candidate genes as revealed by genetic differentiation analyses. Mol. Biol. Evol. 25: 417437 CrossRef
Ford CS, Allainguillaume J, Grilli-Chantler P, Cuccato G, Allender CJ, Wilkinson MJ (2006) Spontaneous gene flow from rapeseed (Brassica napus) to wild Brassica oleracea. P. Roy. Soc. B-Biol. Sci. 273: 3111–3115
Franks SJ, Pratt PD, Dray FA, Simms EL (2008) Selection on herbivory resistance and growth rate in an invasive plant. Am. Nat. 171: 678–691
Gardner, KM, Latta, RG (2006) Identifying loci under selection across contrasting environments in Avena barbata using quantitative trait locus mapping. Mol. Ecol. 15: 13211333 CrossRef
Garnier, A, Deville, A, Lecomte, J (2006) Stochastic modelling of feral plant populations with seed immigration and road verge management. Ecol. Model. 197: 373382 CrossRef
Guehlstorf, NP, Hallstrom, LK (2005) The role of culture in risk regulations: a comparative case study of genetically modified corn in the United States of America and European Union. Environ. Sci. Policy 8: 327342 CrossRef
James C (2005) Preview: Global status of commercialized biotech/GM crops: 2005. ISAAA Briefs 34: Ithaca: ISAAA
Jepson, WE, Brannstrom, C, de Souza, RS (2005) A case of contested ecological modernisation: the governance of genetically modified crops in Brazil. Environ. Plann. C 23: 295310 CrossRef
Kalaitzandonakes, N, Alston, JM, Bradford, KJ (2007) Compliance costs for regulatory approval of new biotech crops. Nat. Biotechnol. 25: 509511 CrossRef
Kane NC, Rieseberg LH (2007) Selective sweeps reveal candidate genes for adaptation to drought and salt tolerance in common sunflower, Helianthus annuus. Genetics 175: 1823–1834
Kannenberg, S, Widmer, A (2008) Ecologically relevant genetic variation from a non-Arabidopsis perspective. Curr. Opin. Plant Biol. 11: 156162 CrossRef
Kent County Council (2000) Kent Red Data Book: A provisional guide to the threatened flora and fauna of Kent. Maidstone: KCC Environmental Management
Lavigne, C, Klein, EK, Vallee, P, Pierre, J, Godelle, B, Renard M (1998) A pollen-dispersal experiment with transgenic oilseed rape. Estimation of the average pollen dispersal of an individual plant within a field. Theor. Appl. Genet. 96: 886896 CrossRef
Lavigne, C, Klein, EK, Mari, JF, Le Ber, F, Adamczyk, K, Monod, H, Angevin, F (2008) How do genetically modified (GM) crops contribute to background levels of GM pollen in an agricultural landscape? J. Appl. Ecol. 45: 11041113 CrossRef
Losey, JE, Rayor, LS, Carter, ME (1999) Transgenic pollen harms monarch larvae. Nature 399: 214 CrossRef
Lu, CF, Kang, JL (2008) Generation of transgenic plants of a potential oilseed crop Camelina sativa by Agrobacterium-mediated transformation. Plant Cell Rep. 27: 273278 CrossRef
Manasse, RS (1992) Ecological risks of transgenic plants - effects of spatial-dispersion on gene flow. Ecol. Appl. 2: 431438 CrossRef
McCartney, HA, Lacey, ME (1991) Wind dispersal from crops of oilseed rape (Brassica napus). J. Aerosol Sci. 22: 467477 CrossRef
Mur LAJ, Carver TLW, Prats E (2006) NO way to live; the various roles of nitric oxide in plant-pathogen interactions. J. Exp. Bot. 57: 489–505 CrossRef
Nasiruddin, KM, Nasim, A (2007) Development of agribiotechnology and biosafety regulations used to assess safety of genetically modified crops in Bangladesh. Symposium on Safety and Adequacy Testing of Foods/Feeds Nutritionally Enhanced Through Biotechnology, July 26, 2006, Gaithersburg, MD. J. Aoac. Int. 90: 15081512
Pandey GK, Cheong YH, Kim KN, Grant JJ, Li LG, Hung W, D'Angelo C, Weinl S, Kudla J, Luan S (2004) The calcium sensor calcineurin B-Like 9 modulates abscisic acid sensitivity and biosynthesis in Arabidopsis. Plant Cell 16: 1912–1924
Pessel, FD, Lecomte, J, Emeriau, V, Krouti, M, Messean, A, Gouyon, PH (2001) Persistence of oilseed rape (Brassica napus L.) outside of cultivated fields. Theor. Appl. Genet. 102: 841846 CrossRef
Pivard, S, Demsar, D, Lecomte, J, Debeljak, M, Dzeroski S (2008a) Characterizing the presence of oilseed rape feral populations on field margins using machine learning. Ecol. Model. 212: 147154 CrossRef
Pivard, S, Adamczyk, K, Lecomte, J, Lavigne, C, Bouvier, A, Deville, A, Gouyon, PH, Huet, S (2008b) Where do the feral oilseed rape populations come from? A large-scale study of their possible origin in a farmland area. J. Appl. Ecol. 45: 476485 CrossRef
Ramjoue, C (2007) The transatlantic rift in genetically modified food policy. J. Agr. Environ. Ethic. 20: 419436 CrossRef
Raybould, A (2007) Ecological versus ecotoxicological methods for assessing the risks of transgenic crops. Plant Sci. 173: 589602 CrossRef
Rodwell JS (1991) British Plant Communities, Vols. 1–5. Cambridge: Cambridge University Press for the Joint Nature Conservancy Council
Roelofs, D, Aarts, MGM, Schat, H, van Straalen, NM (2008) Functional ecological genomics to demonstrate general and specific responses to abiotic stress. Funct. Ecol. 22: 818
Rowland, IR (2002) Genetically modified foods, science, consumers and the media. P. Nutr. Soc. 61: 2529 CrossRef
Saji, H, Nakajima, N, Aono, M, Tamaoki, M, Kubo, A, Wakiyama, S, Hatase, Y, Nagatsu, M (2005) Monitoring the escape of transgenic oilseed rape around Japanese ports and roadsides. Environ. Biosafety Res. 4: 217222 CrossRef
Salleh, A (2006) `Organised irresponsibility': Contradictions in the Australian government's strategy for GM regulation. Env. Politics 15: 399416 CrossRef
Scheffler, JA, Parkinson, R, Dale, PJ (1993) Frequency and distance of pollen dispersal from transgenic oilseed rape (Brassica napus). Transgenic Res. 2: 356364 CrossRef
Sears, MK, Hellmich, RL, Stanley-Horn, DE, Oberhauser, KS, Pleasants, JM, Mattila, HR, Siegfried, BD, Dively, GP (2001) Impact of Bt corn pollen on monarch butterfly populations: a risk assessment. Proc. Natl. Acad. Sci. USA 98: 1193711942 CrossRef
Shaw, MW, Harwood, TD, Wilkinson, MJ, Elliott, L (2006) Assembling spatially explicit landscape models of pollen and spore dispersal by wind for risk assessment. P. Roy. Soc. B-Biol. Sci. 273: 17051713 CrossRef
Stokes KE, Bullock JM, Watkinson AR (2004) Population dynamics across a parapatric range boundary: Ulex gallii and Ulex minor. J. Ecol. 92: 142–155
Tallmon, DA, Luikart, G, Beaumont, MA (2004) Comparative evaluation of a new effective population size estimator based on approximate Bayesian computation. Genetics 167: 977988 CrossRef
Tan, S, Evans, R, Singh, B (2006) Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids 30: 195204 CrossRef
Timmons, AM, Charters, YM, Crawford, JW, Burn, D, Scott, SE, Dubbels, SJ, Wilson, NW, Robertson, A, O'Brien, ET, Squire, G, Wilkinson, M (1996) Risks from transgenic crops. Nature 380: 487 CrossRef
Timmons, AM, O'Brien, ET, Charters, YM, Dubbels, SJ, Wilkinson, MJ (1995) Assessing the risks of wind pollination from fields of genetically modified Brassica napus ssp. oleifera. Euphytica 85: 417423 CrossRef
Turturo, C, Friscina, A, Gaubert, S, Jacquemond, M, Thompson, JR, Tepfer, M (2008) Evaluation of the potential risks associated with recombination in transgenic plants expressing viral sequences. J. Gen. Virol. 89: 327335 CrossRef
Verhoeven, KJF, Poorter, H, Nevo, E, Biere, A (2008) Habitat-specific natural selection at a flowering-time QTL is a main driver of local adaptation in two wild barley populations. Mol. Ecol. 17: 34163424
von der Lippe, M, Kowarik, I (2007a) Crop seed spillage along roads: a factor of uncertainty in the containment of GMO. Ecography 30: 483490 CrossRef
von der Lippe, M, Kowarik, I (2007b) Long-distance dispersal of plants by vehicles as a driver of plant invasions. Conserv. Biol. 21: 986996 CrossRef
Wilkinson MJ, Timmons AM, Charters Y, Dubbels S, Robertson A, Wilson N, Scott S, O'Brien E, Lawson HM (1995) Problems of risk assessment with genetically modified oilseed rape. Brighton Crop Protection Conference 1995 - Weeds 3: 1035–1044
Wilkinson, MJ, Elliott, LJ, Allainguillaume, J, Shaw, MW, Norris, C, Welters, R, Alexander, M, Sweet, J, Mason, DC (2003a) Hybridization between Brassica napus and B. rapa on a national scale in the United Kingdom. Science 302: 457459 CrossRef
Wilkinson, MJ, Sweet, J, Poppy, GM (2003b) Risk assessment of GM plants: avoiding gridlock? Trends Plant Sci. 8: 208212 CrossRef
Wilson, WW, Henry, X, Dahl, BL (2008) Costs and risks of conforming to EU traceability requirements: The case of hard red spring wheat. Agribusiness 24: 85101 CrossRef
Yoshimura, Y, Beckie, HJ, Matsuo, K (2006) Transgenic oilseed rape along transportation routes and port of Vancouver in western Canada. Environ. Biosafety Res. 5: 6775 CrossRef
Yusuf, MA, Sarin, NB (2007) Antioxidant value addition in human diets: genetic transformation of Brassica juncea with gamma-TMT gene for increased alpha-tocopherol content. Transgenic Res. 16: 109113 CrossRef
Zafar, Y (2007) Development of agriculture biotechnology in Pakistan. Symposium on Safety and Adequacy Testing of Foods/Feeds Nutritionally Enhanced Through Biotechnology, July 26, 2006, Gaithersburg, MD. J. Aoac. Int. 90: 15001507